Diabetes Flashcards

1
Q

What blood glucose level is hypoglycaemia?

A

<4mmol/L

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2
Q

Define the clinical classification of severe hypoglycaemia

A

Needs parenteral therapy

Coma/seizure

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3
Q

Define mild hypoglycaemia

A

Symptomatic glycaemia that resolves with self treatment

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4
Q

Define biochemical hypoglycaemia

A

Plasma glucose <4.0 with no symptoms

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5
Q

How do you treat mild hypoglycaemia in a patient who is awake and talking?

A

Give dextrosol tablets

Avoid fruit juice in patients with renal disease

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6
Q

How do you treat moderate hypoglycaemia in a patient who is semi-conscious and able to swallow?

A

Give 1.5 to 2 tubes of glucose gel

If this is ineffective - give 1mg of glucagon IM

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7
Q

How do you treat severe hypoglycaemia in the unconscious patient?

A

GET SENIOR HELP

Stop any IV insulin

If IV access available - give 75ml 20% glucose or 150ml of 10% glucose

If no IV access - 1mg of glucagon

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8
Q

How should you assess someone after they have recovered from a hypoglycaemic episode?

A

Ask when patient last ate
Check dosage of insulin including time given at
Check for signs of lipohypertrophy
Check credibility of blood glucose monitoring

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9
Q

What are the driving rules for being diabetic?

A

Check glucose prior to driving and every 2hrs

Keep a source of glucose and meter in the vehicle

Do not drive if glucose <5mmol/L

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10
Q

Define diabetic ketoacidosis

A

A disordered metabolic state that usually occurs in the context of an absolute or relative insulin deficiency accompanied by an increase in the counter-regulatory hormones i.e. glucagon, adrenaline, cortisoleand growth hormone

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11
Q

What does hyperglycaemia lead to?

A

Glycosuria
Electrolyte loss
Dehydration
Reduced renal function

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12
Q

How does ketoacidosis occur?

A

Insulin deficiency -> stress hormone activation -> increased lipolysis -> incrased FFA to liver -> ketoacidosis and increased lactate

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13
Q

Define ketonaemia

A

> 3mmol/L

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14
Q

Define ketonuria

A

> 2+ on a dipstick

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15
Q

Define hyperglycaemia

A

> 11.0mmol/L

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16
Q

Define DKA biochemically

A

Ketonaemia or significant ketonuria

BG > 11mmol/L

Bicarbonate <15mmol/L or venous pH <7.3

17
Q

What are some of the osmotic related symptoms?

A

Thirst
Polyuria
Dehydration

18
Q

Give some ketone symptoms and signs

A

Flushed
Vomiting
Abdominal pain and tenerness
Breathless - Kussmaul’s respiration

19
Q

Give some classic biochemistry signs of diabetic ketoacidosis

A

Glucose high (median level 40mmol/L)

Potassium >5.5mmol/L

Creatinine high

Sodium Low

Lactate high

High ketones

Low bicarbonate

Raised amylase

High WCC

20
Q

What is HbA1c?

A

Average BG for the last 2-3 months

21
Q

What is an ideal HbA1c?

A

<48mmol/mol