Diabetes Flashcards
What do Biguanides do? Example: Metformin
- Decrease hepatic glucose production
- Augments glucose reuptake by tissues
What is an important thing to know about Biguanides?
What is a side effect?
- Hold 1-2 days before any tests involving IV CONTRAST
- Diarrhea, Lactic Acidosis
What do Sulfonyreas do?
Example: Glipizide, glyburide, and glimepiride
What are their side effects?
- Stimulates the Secretion of Insulin in the Pancreas
- Enhances cellular sensitivity to insulin
-Weight gain, Hypoglycemia
What do Meglitinides do?
Ex. Nateglinides and Repaglinides
What are their side effects?
- Stimulate a rapid and short lived release of insulin from the pancreas
- Weight Gain, Hypoglycemia
What do Alpha-Glucosidase Inhibitors do?
Ex. Arcabos and Miglitol
Side effects?
- Delay absorption of complex carbohydrates from GI Tract
- Gas, Abdominal Pain, Diarrhea
What do Thiazolidnediones do?
Ex. Pioglitazone, Rosiglitazone
Side Effects?
- Increase glucose re-uptake in muscle
- Decrease endogenous glucose production
-Weight Gain, Edema
What is the drug interaction between Beta Blockers and Hypoglycemics?
Thiazide and Loop Diuretics and Hypoglycemics?
- Beta Blockers can mask the effects of hypoglycemia and prolong the hypoglycemic effects of insulin
- Diuretics can help cause hypoglycemia by inducing potassium loss
What should the plan for people with Type 1 DM be?
What should the teachings be
- Work with their usual intake
- Take into account their exercise pattern
Teachings
- Fixed Insulin Regimen
- Routine of time of Insulin, calories, and exercise
- Allow client to be more flexible and know exactly how much insulin to give themselves when on rapid acting or insulin pump
What should the plan for people with Type 2 DM be?
What should the teachings be
- Emphasis based on ACHIEVING TARGET GLUCOSE, LIPIDS, and BP
- Calories and Fat Reduction
Teachings -Nutritionally adequate diet (Decreased saturated fats and sugars) -Space out meals -Regular exercise and lifestyle changes
What factors can increase blood glucose and how does it due this?
Physical and Emotional Stress can increase Blood Glucose due to Cortisol
What do you do if you have DM and are ill or under stress?
- Continue regular meal plan
- Continue taking medications as prescribed
- Check BG every 4 hours
- If sugar is >240 check ketones
What is the definition of low blood sugar?
What organ system will this effect the most and why/
Blood sugar < 70
The brain will be most effected because it only relies on glucose for energy
-Other cells can convert protein and fat into energy but not the brain
What are signs of hypoglycemia?
Confusion Irritability Diaphoresis - excess sweating -Tremors -Hunger -Weakness Visual Disturbances
Which population are vulnerable to HYPOGLYCEMIC UNAWARENSS (not recognizing the signs and symptoms of hypoglycemia)
What do you do?
- Those with Neuropathy
- The Elderly
- Beta Blocker Users
Manage them a little on the high side of blood glucose
What are some causes of hypoglycemia?
- To Much Insulin
- Too Little Food
- Too Much Exercise
-Mismatch of Food Intake and Peak Insulin Times
What should you do after you assess the patient?
If BS > 70, begin assessing for other causes
If BS < 70, GIVE 15 - 20 mg of simple sugars (juice, soda, ect.) Then Re-Assess 15 minutes later, Follow up with complex carbs after BS >70