Diabetes Flashcards

1
Q

What is type 1 diabetes?

A

An absolute deficiency of insulin

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2
Q

What is type 2 diabetes?

A

Resistance to insulin action &an inadequate compensatory insulin secretory response

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3
Q

Where is glucose absorbed from?

A

small intestine into the blood

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4
Q

Where is an increase in concentration of blood glucose sensed by?

A

Beta-cells of the pancreas

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5
Q

Where do glucose transporters facilitate uptake of glucose for storage as glycogen?

A

The liver

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6
Q

what fasted plasma glucose level is diabetic?

A

> 7.0mmol/L

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7
Q

What random plasma glucose level is diabetic?

A

> 11.1mmol/L

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8
Q

What are symptoms of diabetes?

A

Increases thirst, increased nee to urinate, fatigue, tiredness, weight loss and blurred vision

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9
Q

Are symptoms more severe and set on faster in type 1 or 2 diabetes?

A

Type 1

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10
Q

What is the current prevalence of diabetes in the uk?

A

3.4 million

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11
Q

What is the aetiology of type 1 diabetes?

A

Autoimmune destruction on beta-cells, can occur at any age, famalilia trend, viruses, drugs or cehmical

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12
Q

What disorders is type 1 diabetes secondary to?

A

Pancreatitis

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13
Q

What % of type 2 diabetics are obese?

A

80%

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14
Q

How can type 2 diabetes be treated?

A

Lifestyle modification, oral hypoglycaemic agents or exogenous insulin therapy

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15
Q

How many years before diagnosis is type 2 diabetes detectable by?

A

10 Years

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16
Q

Name three identifications of metabolic syndrome?

A

blood pressure>130/>85 mm HG, Fasting glucose >6.1mmol/l and serum triglycerides >1.7mmol/l

17
Q

What health outcomes can diabetes cause?

A

Neuropathy, Nepthropathy, retinopathy and microvascular complications

18
Q

What is associated with diabetic complications?

A

Length of diabetes duration

19
Q

What for of diabetes is more relevant to macrovascular complications?

A

Type 2

20
Q

What macrovascualr complications can type2 diabetes cause?

A

Coronary heart disease, stroke, peripheral vascular disease and increased morality

21
Q

What should type 2 diabetes aim to control?

A

Lipid factors and blood pressure

22
Q

What blood glucose level is hypoglycemic (glucose deficient) when self monitoring?

A

< 4.0 mmol/l

23
Q

What blood glucose level is hyperglycaemic (excessive glucose) when self monitoring?

A

persistently >12.0 mmol?l

24
Q

Normal blood glucose level before meals?

A

4-7 mmol/l

25
Q

what treatment is required for type 1 diabetics?

A

Insulin therapy, pump therapy, carbohydrate counting and insulin bd

26
Q

How often a day should T2 diabetics measure blood glucose?

A

once a day

27
Q

How many times per day should T1 diabetics check blood glucose levels?

A

pre breakfast, lunch, dinner and before bed