Diabetes Flashcards
What is type 1 diabetes?
An absolute deficiency of insulin
What is type 2 diabetes?
Resistance to insulin action &an inadequate compensatory insulin secretory response
Where is glucose absorbed from?
small intestine into the blood
Where is an increase in concentration of blood glucose sensed by?
Beta-cells of the pancreas
Where do glucose transporters facilitate uptake of glucose for storage as glycogen?
The liver
what fasted plasma glucose level is diabetic?
> 7.0mmol/L
What random plasma glucose level is diabetic?
> 11.1mmol/L
What are symptoms of diabetes?
Increases thirst, increased nee to urinate, fatigue, tiredness, weight loss and blurred vision
Are symptoms more severe and set on faster in type 1 or 2 diabetes?
Type 1
What is the current prevalence of diabetes in the uk?
3.4 million
What is the aetiology of type 1 diabetes?
Autoimmune destruction on beta-cells, can occur at any age, famalilia trend, viruses, drugs or cehmical
What disorders is type 1 diabetes secondary to?
Pancreatitis
What % of type 2 diabetics are obese?
80%
How can type 2 diabetes be treated?
Lifestyle modification, oral hypoglycaemic agents or exogenous insulin therapy
How many years before diagnosis is type 2 diabetes detectable by?
10 Years