Diabetes

Question 1

What medication is used to treat type 2

Answer 1

Metaformin, enhances cell insulin sensitivity and reduce hepatic gluconeogenesis

DDP-4 inhibtirs (Gliptins) t oblock enzyme metabolising incretin

GLP-1 mimetics to increase level of incretin

Sulphonylureas to increase pancreatic insulin secretion

Question 2

What 2 froms of a diabetes is there

Answer 2

Mellitus and insipidus

Question 3

What is diabetes mellitus

Answer 3

abnormality of GLUCOSE regulation

Question 4

What is diabetes insipidus

Answer 4

abnormality of RENAL FUNCTION (WATER)

Question 5

In a random plasma glucose what score is diagnostic of diabetes

Answer 5

> 11.1mmol/L on 2 occasions

Question 6

What is a HbA1C test for

Answer 6

Used to diagnose type 2 diabetes and monitor blood glucose control in people with diabetes

Question 7

What HbA1C test score is indicitive of diabetes

Answer 7

HbA1C< 48mmol/mol (6.5%)

Question 8

In a glucose tolerance test (75g load after fasting) what scores would be indicitive of diabetes

Answer 8

Before test (mmol/L)
FPG <6.1 Normal

FPG >7.0 Diabetes

2 hour plasma glucose (mmol/L)
<7.8 normal

> 11.1 Diabetes

Question 9

What happens in type 1

Answer 9

Insulin deficency

Autoimmune destruction of pancreatic B cells

Question 10

What happens in type 2

Answer 10

defective and delayed insulin secretion and abnormal postprandial suppression of glucagon