Diabetes Flashcards
What is diabtes?
Chronic condition characterized by hyperglycemia
What is decreased in diabetes?
Insulin
What is elevated in diabetes
Glucagon, epinephrine, cortisol, hGH
Prevalence of diabetes in..
50 y/o
Diabetes type 1
<30 years
Autoimmune disease: the body attacks the beta cells
Genetic and Environment factors
Treatment: insulin, diet, exercise
Environmental factores for T1 Diabetes
Virus: coxsackie, pox virus, rubella
Nutrients: cow milk
Diabetes type 2
> 40 year olds
Habits are factors
Tissue’s receptors becomes resistant of insulin
Treatment: diet, exercise, oral hypoglycemics, insulin
Preventable and Most common diabetes
T2
Normal metabolic pathways after eating
Liver: glycogen synthesis
Adipose: lipogenesis
Muscle: protein synthesis
Metabolic pathways after eating in diabetes
Liver: glucose released
Adipose: lipolysis
Muscle: proteolysis
Diabetes symptoms
- Fatigue - no energy
- Polyphagia - they feel like they are starving
- Leaking of glucose through the kidney
They pee more (polyuria)
They are more thirsty (polydipsia)
Acute diabetes complications
*Hypoclycemia
*Ketoacidosis
*Non keto hyper osmolar state
Chronic Vascular complications in diabetes
Microangiopathy: retinopathy, nephropathy, neuropathy
Macroangipathy: coronary, cardiovascular and peripheral vascular disease
Chronic Non-vascular complications in diabetes
- Gastroparesis
- Eual dysfunction
- Skin dehydration
Diagnostic criteria ADA
- Fasting: ≥ 126 mg/dl
- Posprandial: ≥ 200 mg/dl
- HbA1C: ≥ 6.5 %