Diabetes Flashcards
DPP-4 inhibitors = gliptins
Monitoring
LFT +UE
DPP-4 inhibitors = gliptins
Weight change?
Hypoglycaemia
Weight neutral
No hypoglycaemia
DPP-4 inhibitors = gliptins
Mechanism
Reduced glucagon release from pancreas
DPP-4 inhibitors = gliptins
Contraindications? (4)
Ketoacidosis
Liver impairment
Heart failure
Pancreatitis
Pioglitazone
Monitoring
LFT
Pioglitazone
Mechanism
Reduced peripheral insulin resistance
Pioglitazone
Weight change and hypoglycaemia
Increase in weight
No hypoglycaemia
Pioglitazone
Contraindications (3)
Heart failure
Bladder Ca/haematuria
Liver impairment
Pioglitazone
Side effects
Fractures
Peripheral oedema
Sulfonylureas = gliclazide
Mechanism
Increased insulin release from pancreas
Sulfonylureas = gliclazide
Weight and hypoglycaemia
Increased weight
Hypoglycaemia
Sulfonylureas = gliclazide
Weight and hypoglycaemia
Increased weight
Hypoglycaemia
Sulfonylureas = gliclazide
Contraindications
Acute porphyria
Ketoacidosis
Severe renal/liver impairment
Obesity
Sulfonylureas = gliclazide
Side effect
Hypoglycaemia
Cholestasis
Sulfonylureas = gliclazide
Side effect
Hypoglycaemia
Cholestasis