DI 2 Final - Tumor Flashcards

1
Q

what’s the most common source of osteoblastic metastatic carcinoma in adult F?

A

Breast CA

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2
Q

3 common causes of solitary sclerotic (ivory) vertebral body!

A
  1. Hodgkin’s lymphoma
  2. Osteoblastic metastatic**
  3. Paget’s dz
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3
Q

Is it common to find a tumor involving a jt?

A

NO

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4
Q

Is multiple myeloma more common in the vertebral body or neural arch?

A

Vertebral body!

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5
Q

What malignancy demonstrates as a cold bone scan?

A

Multiple myeloma

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6
Q

Which is the most dense primary malignant bone tumor?

A

Multiple myeloma 1st

2nd - osteosarcoma
3rd - condroscarcoma (kid)
4th - ewing’s (kid)

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7
Q

What’s the common age range of primary osteosarcoma?

A

10-25 y/o

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8
Q

What’s the difference btwn sunburst & onion skin appearance?

A

Sunburst: periosteal spokes of wheel pattern (skull lesions, lytic, osteosarcoma)

Onion: layered/laminated periosteal, Ewing’s tumor

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9
Q

Which part of the bone is commonly involved in osteosarcoma?

A

Metaphysis of long bone (distal femur, prox tibia/humerus)

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10
Q

What’s codman’s triangle?

A

Periosteal bone formation interrupted/incompletely cover surface of lesion (periosteum lifts off cortex) - osteosarcoma

–Triangle: several layers of periosteal rxn at lesion - avoid for Bx

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11
Q

Why is Ewing’s sarcoma commonly found in diaphysis of long bone?

A

Red BM - diaphysis, reticulum cell sarcoma

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12
Q

What’s geographic appearance?

A

confined to relatively specific area, easily defined, benign

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13
Q

Which condition presents w/solitary exostosis that points away from nearest joint?

A

Osteochondroma

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14
Q

What’s the radiographic difference in appearance btwn osteochondroma & benign solitary expansile osteolysis?

A

Osteochondroma: Bony exostosis: cortex continueous w/host bone, pedunculated, calcify cartilage cap, projects AWAY from jt

Benign Solitary: expansile, large, lytic, separated, thin cortex, ONLY TUMOR CROSSES GROWTH PLATE

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15
Q

Incidence of malignant transformation in osteochondroma & hereditary multiple exostosis?

A

Osteochondroma: 1%
HME: 20%

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16
Q

Corduroy Vertebra?

A

Lytic lesion w/coarse vertical striation (1-2 vertebral bodies)
W/hemangiomas

17
Q

Spinal hemangioma… solitary/polyostotic?

A

Soitary

18
Q

Most common benign bone tumor of spine?

A

Hemangioma

19
Q

Is a bone island (endostoma) symptomatic?

A

NO (except skull)

20
Q

Which condition demonstrats pain worse at night, relieved by aspirin?

A

Osteoid Osteoma (benign)

21
Q

Which part of bone involved w/osteoid osteoma?

A

Any bone - cortical**

22
Q

What is the appearance of the tumor matrix in enchondroma?

A

Geographic lytic, expansile, matrix calcification, thinned cortex, central, no ST mass

23
Q

Why is it common to observe a short limb w/enchondroma?

A

Tumor of hands/feet/phalanges

24
Q

Whats multiple enchondromatosis?

A

Ollier’s dz

25
Q

What’s most common location of fibrous cortical defect?

A

LE (90% tib/fib)

26
Q

What’s fallen fragment sign?

A

2/3 simple bone cysts undergo pathologic fx – piece of bone below patho fx

27
Q

Which benign bone tumor named according to appearance rather than histo composition?

A

Aneurysmal bone cyst (cystic, blood filled cavity)

28
Q

Radiographic description of Enchondroma?

A

Sml round/oval cystic defects
Matrix calcification
Endosteal scalloping
Islands of cartilage surrounded by layers of bone

29
Q

Radiographic description of simple bone cyst?

A

Oblong, central, expansile
Radiolucent, subepiphyseal osteolytic lesion
Fallen fragment

30
Q

Radiographic description of Aneurysmal bone cyst?

A

Osteolytic, soap bubble, expansile

Thin cortices, cavities filled w/blood

31
Q

Radiographic description of Osteochondroma?

A

Sessile or pedunculated
Coat hanger exostosis or cauliflower cap
ABN outgrowth lateral growth plate
Epihyseal growth

32
Q

Is giant cell tumor painful?

A

YES

33
Q

Is paget’s dz mono/polystotic?

A

Polyostotic

34
Q

Radiographic descirption of paget’s dz?

A
Coarse (thick, less distinct) trabeculae
Thick cortex
Bone expansion
Pseudo-Fx
Deformities
Skull: osteoporosis, cottonwool
Spine: picture frame vertebrae, ivory
Pelvis: brim/rim sign
Femur/Tibia: blade of grass, candle frame, shepard's crook