DI 2 Final - Tumor Flashcards
what’s the most common source of osteoblastic metastatic carcinoma in adult F?
Breast CA
3 common causes of solitary sclerotic (ivory) vertebral body!
- Hodgkin’s lymphoma
- Osteoblastic metastatic**
- Paget’s dz
Is it common to find a tumor involving a jt?
NO
Is multiple myeloma more common in the vertebral body or neural arch?
Vertebral body!
What malignancy demonstrates as a cold bone scan?
Multiple myeloma
Which is the most dense primary malignant bone tumor?
Multiple myeloma 1st
2nd - osteosarcoma
3rd - condroscarcoma (kid)
4th - ewing’s (kid)
What’s the common age range of primary osteosarcoma?
10-25 y/o
What’s the difference btwn sunburst & onion skin appearance?
Sunburst: periosteal spokes of wheel pattern (skull lesions, lytic, osteosarcoma)
Onion: layered/laminated periosteal, Ewing’s tumor
Which part of the bone is commonly involved in osteosarcoma?
Metaphysis of long bone (distal femur, prox tibia/humerus)
What’s codman’s triangle?
Periosteal bone formation interrupted/incompletely cover surface of lesion (periosteum lifts off cortex) - osteosarcoma
–Triangle: several layers of periosteal rxn at lesion - avoid for Bx
Why is Ewing’s sarcoma commonly found in diaphysis of long bone?
Red BM - diaphysis, reticulum cell sarcoma
What’s geographic appearance?
confined to relatively specific area, easily defined, benign
Which condition presents w/solitary exostosis that points away from nearest joint?
Osteochondroma
What’s the radiographic difference in appearance btwn osteochondroma & benign solitary expansile osteolysis?
Osteochondroma: Bony exostosis: cortex continueous w/host bone, pedunculated, calcify cartilage cap, projects AWAY from jt
Benign Solitary: expansile, large, lytic, separated, thin cortex, ONLY TUMOR CROSSES GROWTH PLATE
Incidence of malignant transformation in osteochondroma & hereditary multiple exostosis?
Osteochondroma: 1%
HME: 20%
Corduroy Vertebra?
Lytic lesion w/coarse vertical striation (1-2 vertebral bodies)
W/hemangiomas
Spinal hemangioma… solitary/polyostotic?
Soitary
Most common benign bone tumor of spine?
Hemangioma
Is a bone island (endostoma) symptomatic?
NO (except skull)
Which condition demonstrats pain worse at night, relieved by aspirin?
Osteoid Osteoma (benign)
Which part of bone involved w/osteoid osteoma?
Any bone - cortical**
What is the appearance of the tumor matrix in enchondroma?
Geographic lytic, expansile, matrix calcification, thinned cortex, central, no ST mass
Why is it common to observe a short limb w/enchondroma?
Tumor of hands/feet/phalanges
Whats multiple enchondromatosis?
Ollier’s dz
What’s most common location of fibrous cortical defect?
LE (90% tib/fib)
What’s fallen fragment sign?
2/3 simple bone cysts undergo pathologic fx – piece of bone below patho fx
Which benign bone tumor named according to appearance rather than histo composition?
Aneurysmal bone cyst (cystic, blood filled cavity)
Radiographic description of Enchondroma?
Sml round/oval cystic defects
Matrix calcification
Endosteal scalloping
Islands of cartilage surrounded by layers of bone
Radiographic description of simple bone cyst?
Oblong, central, expansile
Radiolucent, subepiphyseal osteolytic lesion
Fallen fragment
Radiographic description of Aneurysmal bone cyst?
Osteolytic, soap bubble, expansile
Thin cortices, cavities filled w/blood
Radiographic description of Osteochondroma?
Sessile or pedunculated
Coat hanger exostosis or cauliflower cap
ABN outgrowth lateral growth plate
Epihyseal growth
Is giant cell tumor painful?
YES
Is paget’s dz mono/polystotic?
Polyostotic
Radiographic descirption of paget’s dz?
Coarse (thick, less distinct) trabeculae Thick cortex Bone expansion Pseudo-Fx Deformities Skull: osteoporosis, cottonwool Spine: picture frame vertebrae, ivory Pelvis: brim/rim sign Femur/Tibia: blade of grass, candle frame, shepard's crook
