Devlin: Corneal Crosslinking

Question 1

What are the 4 characteristics of keratoconus?

Answer 1

1. Progressive Corneal Thinning
2. Irregular Topography
3. Eventual Scarring
4. Visual Compromise

Question 2

What are the 5 txs for keratoconus?

Answer 2

1. Glasses
2. Soft CLs
3. Hard CLs
4. Collagen CxL
5. Corneal Transplant

Question 3

What guides the tx options for a keratocone?

Answer 3

1. The patient
2. Intolerance to CLs
3. Corneal Clarity
4. Corneal Shape

Question 4

Collagen CxL is intended to halt the progression of what disease?

Answer 4

Ectasia

Question 5

What are the 2 components of collagen crosslinking?

Answer 5

UV light + Riboflavin (vit b12)

- it “ages” the cornea

Question 6

What are the indications for collagen cxl?

Answer 6

1. Keratoconus
2. Ectasia
3. PMD/Rx sx induced
4. Scarring from infection

Question 7

What are the risks for collagen cxl?

Answer 7

1. Infection
2. Corneal haze/scar
3. Decreased acuity
4. Ineffective

Question 8

What is the only FDA approved version for collagen cxl?

Answer 8

Avedro KXL System

Question 9

What is the ideal patient for collagen cxl?

Answer 9

1. Early KCone
2. Good acuity
3. Clear cornea
4. Young

Question 10

What is a corneal inlay?

Answer 10

Small, instrastromal device intended for presybopic patients

Question 11

Name the 3 types of corneal inlays

Answer 11

1. Acufocus Karma
2. Raindrop
3. Flexivue

Question 12

Which corneal inlay is a reversible procedure?

Answer 12

Acufocus

Question 13

What’s the size of the acufocus?

Answer 13

3.8mm diameter

Question 14

What’s the size of the raindrop?

Answer 14

2mm diameter

Question 15

How does the Raindrop work?

Answer 15

1. Reshapes extreme anterior portion of cornea

2. Central cornea = near, gradual blend to distance at periphery

Question 16

What is the photopic and scotopic pupil size needed for Raindrop?

Answer 16

Photopic = > 3mm
Scotopic = >7mm