Developmental Disorders

Question 1

Failure of neural tube closure at the rostral end results in what?

Answer 1

Anencephaly

Question 2

Failure of neural tube closure at the caudal end results in what?

Answer 2

Spina bifida

Question 3

What have imaging studies reveled about children with ASD?

Answer 3

• Have larger brains
• Increased amounts of white and gray matter
• Excessive amounts of cerebrospinal fluid (CSF)

-Hemispheric asymmetry

Question 4

What have imaging studies revealed about children with Down Syndrome?

Answer 4

• Have smaller brains
• Particularly smaller FL, TL, cerebellum and hippocampus
• Fewer neurons overall, fewer synapses, and less dendritic branching

Question 5

What is fragile X syndrome?

Answer 5

Reduced synaptogenesis and synaptic plasticity