Development of the Tooth and its supporting tissue

Question 1

all organs develop from

Answer 1

epithelium and

Question 2

intracrine

Answer 2

produce in nuclesus and goes right back in without leaving the cell

Question 3

induction influence is in the epithelial layer: influencing underlying mesenchyme to become a tooth

Answer 3

.

Question 4

Cranial neural crest and nerves form:

Answer 4

• ganglia and nerves
• adrenal medulla
• ectomesenchyme of bones and teeth (all but enamel)

Question 5

six stage of crown development

Answer 5

• initiation
• bud
• cap
• bell
• apposition
• maturation

Question 6

what is happening during initiation stage

Answer 6

induction

Question 7

what is happening during bud stage

Answer 7

proliferation

Question 8

what is happening during cap stage

Answer 8

proliferation, differentiation, morphogenesis

Question 9

what is happening during bell stage

Answer 9

proliferation, differentiation, morphogenesis

Question 10

what is happening during apposition stage

Answer 10

induction and proliferation

Question 11

what is happening during maturation stage

Answer 11

maturation

Question 12

in bud stage, each bud is a precursor of

Answer 12

enamel organ for each deciduous tooth

Question 13

In bud stage, what stimulates the mesenchyme to transcription factors

Answer 13

BMP-4, Fgf-8, Lef-1

Question 14

in bud stage, there are ___ locations along each dental lamina, ____ of epithelium produces buds

Answer 14

ten, proliferation

Question 15

in initiation stage, what stimulates pre-dental ectoderm to produce Fgf-8

Answer 15

Lef-1

Question 16

in initiation stage, what induces mesenchyme to express Pax-9 and Msx-1

Answer 16

Fgf-1

Question 17

in initiation stage, what inhibits Fgf-8

Answer 17

BMP-2 and 4

Question 18

what happens in Cap stage?

Answer 18

ectomesenchyme cells condense around developing cap

Question 19

in cap stage, what becomes the dental papilla and dental sac?

Answer 19

ectomesenchyme

Question 20

tooth germ = ?

Answer 20

enamel organ, dental papilla, dental sac

Question 21

successional dental lamina forms on____ of dental lamina

Answer 21

lingual side

Question 22

the cap stage is

Answer 22

unequal proliferation of bud cells cause a cap to form

Question 23

bell stage is

Answer 23

continued differntiation of enamelorgan produces four distinctlayer with different function

Question 24

in bellstage, how many layers are there

Answer 24

4

Question 25

what are the four layers of bell stage

Answer 25

• outer enamel epithelium
• stellate reticulum
• stratum intermedium
• inner enamel epithelium

Question 26

in the bell stage, what is the cervical loop consist of

Answer 26

junction of OEE and IEE

Question 27

in the bell stage, what does the dental papilla cells continue to proliferate into:

Answer 27

outer dental papilla cells

inner dental papilla cells

Question 28

in the bell stage, what does the dental sac cells develop into later?

Answer 28

periodontal tissues

Question 29

role of outer enamel epithelium

Answer 29

protective barrier for enamel organ

Question 30

role of stellate reticulum

Answer 30

support enamel production

Question 31

role of stratum intermedium

Answer 31

supports enamel mineralization -alkaline phasphatase

Question 32

role of inner enamel epithelium

Answer 32

differentiate into ameloblasts

Question 33

what is happening in the apposition stage

Answer 33

organic matrix ofenamel and dentin are laid down foloowed by initial calcification

Question 34

in apposition stage the IEE differentiate into__1___, the -

Answer 34

preameloblasts

Question 35

preameloblast induce ____ cells too differentiate into preodontoblast

Answer 35

dental papilla

Question 36

preodontoblasts continue to differentiating into

Answer 36

odontoblast

Question 37

in the apposition stage, the DEJ forms after

Answer 37

disintegration of basement membrane

Question 38

what is prismless enamel formed by

Answer 38

early secretory ameloblast

Question 39

enamel prisms are formed by

Answer 39

Tomes processes of late secretory ameloblast

Question 40

in apposition stage, predentin induces differentiation of

Answer 40

preameloblasts into ameloblasts

Question 41

in apposition stage, ameloblastbegin secreting enamel matrix whcih immediately califies to ___ of full mineralization

Answer 41

25%

Question 42

what are the seven stages of the ameloblasts

Answer 42

• inner enamel epithelial cell
• preameloblast (cell reverses polarity)
• Initial secretory ameloblast (no tomes process)
• secretory ameloblast (tomes process)
• Smooth-ened maturation ameloblast (remove of protein/h20
• ruffled ended maturation ameloblast -intro inorganic material
• protective ameloblast- enamel cuticle