Cyto, junctions, fibroblast, ECM

Question 1

name three cytoskeletal components

Answer 1

microfilaments
intermediated filaments
microtubules

Question 2

Zonula Adherens role

Answer 2

holds cells to together

Question 3

location of Cadherins

Answer 3

Outside

Question 4

location of Catinis

Answer 4

Inside

Question 5

Cadherins are _____ dependent

Answer 5

Ca2+

Question 6

what attaches to Actin filaments

Answer 6

Vinculin and Actinin

Question 7

role of focal adhesion junction

Answer 7

hold cells to extracellular matrix

stick cells to matrix

Question 8

trans-membrane component of Focal adhesion junction

Answer 8

Integrins

Question 9

role of integrin receptors

Answer 9

cell signaling

Question 10

desmosomes role

Answer 10

cell to cell adhesion

Question 11

cadherins are associated with

Answer 11

desmoglein and desmocollin

Question 12

Catininare associated with

Answer 12

desmoplakin, plakoglobin and plakophilin

Question 13

type of interaction of desmoglein and desmocollin

Answer 13

heterotypical interaction

Question 14

what does desmosomes help resist

Answer 14

shearing force

Question 15

role of hemidesmosomes

Answer 15

cell-matrix adhesion

Question 16

what does hemidesmosomes attach to

Answer 16

intermediate filaments

Question 17

what does hemidesmosomes use to attach to the basal lamina

Answer 17

integrin-laminin and collagen XVII

Question 18

whatare gap junctions

Answer 18

cell to cell aqueous pores

Question 19

6X connexins =

Answer 19

1x connexon

Question 20

gap junctions can also

Answer 20

propagate electrical signals

Question 21

role of basal lamina

Answer 21

ECM sheet attaching epithelium to connective tissue

Question 22

three zones of basal lamina

Answer 22

lam. lucida -integrins
lam. desna -collagen
lam fibroreticularis (not in all)- depends, col III

Question 23

role of fibroblast

Answer 23

cell of connective tissue

highly motile, involved in tissue repair (slower in age)

Question 24

often have ______ connections from _____ to fibronection the ECM

Answer 24

cytoskeletal (actin), integrins

Question 25

structure of collagen

Answer 25

triple helical

Question 26

collegen is rich in

Answer 26

proline and lysine

Question 27

dentine is mostly

Answer 27

type I andsome type III

Question 28

pulp is mostly

Answer 28

mix of type I and III

Question 29

cartilage is

Answer 29

type II

Question 30

Elastin has a ____ for support

Answer 30

glycoprotein scaffold (fabrillin 1 and 2)

Question 31

connective tissue ground substance is made up mostly of

Answer 31

proteoglycans and glycoproteins

Question 32

proteoglycan is made by

Answer 32

fibroblast

Question 33

structure of proteoglycan

Answer 33

protein core with glcosaminoglycan chains (GAGs)

Question 34

proteoglycans can serve to

Answer 34

sequester growth factors in ECM and can help activate GF receptors

Question 35

microfilaments are made of ____, are ____ in diameter

Answer 35

actin and 6-8 nm

Question 36

roleof microfilaments

Answer 36

stucture function, microvilli, filopodia, gives shapeto cell

Question 37

role of intermediate filaments

Answer 37

anchors cell, structure

Question 38

main compontent of microtubules

Answer 38

tubulin

Question 39

name the cell attachments

Answer 39

tight junctions
adhesive junctions-zonula adherens
focal adhesion junctions
desmosomes
hemidesmosomes
gap junctions

Question 40

role of tight junctions

Answer 40

various cell signaling pathways

Question 41

proteins associated with tight junctions and job

Answer 41

claudins, occludin, JAM

bind to actin microfilaments

Question 42

heterotypical interaction of desmoglein and desomocollin

Answer 42

desmosomes