Development, Molecular Biology, and Physiology of the Prostate

Question 1

The prostate is a derivative

Answer 1

primitive endoderm (gut tube

Question 2

the cloaca divides during__ to create separate __ and ___

Answer 2

embrygenesis urogenital digestive outlets

Question 3

ventral urinary compartment is called

Answer 3

primitive urogenital sinus

Question 4

Prostate organogenesis occurs in four overlapping stages: 1. ___ exposure of the urogenital sinus directly or indirectly initiates the first stage, prostate lineage commitment of regions of the urogenital sinus epithelium.

2. In the second stage, solid cords epithelial cords, or prostate buds, form and invade _____ at stereotyped locations that pattern the future development of distinct prostate lobes in the rodent and, potentially, zones in the human.
3. In the third stage of prostate organogenesis, ___ __ and __ to form the mature prostate network, (postnatal days 1 to 14 in mice) as part of a sophisticated branching morphogenesis program
4. Finally, the ducts ___, and ___ of the epithelium results in mature prostate glands

Answer 4

1. Androgen
2. urogenital sinus mesenchyme
3. In the third stage of prostate organogenesis, prostate buds elongate and branch to form the mature prostate network, (postnatal days 1 to 14 in mice) as part of a sophisticated branching morphogenesis program
4. Finally, the ducts __, and ___ of the epithelium results in mature prostate glands