Developing New Drugs Flashcards
Starts by searching for compounds that interrupt _
Disease pathways
Disease pathways are a set of chemical reactions that cause disease or _
Symptoms
Some compounds found in nature, while others are _ and then synthesized in a lab
Designed on computer
- Identify pathways
Researchers begin by studying disease. In most cases, this involves searching for
Set of proteins produced by pathogen
- Identify pathways
Searching for set of proteins produced by pathogens, or by _
Body itself
- Identify pathways
It is the interaction between these proteins, called a pathway, that _
Cause the disease or symptoms
- Search for compounds
Researchers look for compounds that interrupt the disease pathways by _
Binding directly to the target protein
- Search for compounds
Find compounds that interrupt disease pathways by trying thousands of possible compounds in lab or by designing _ then synthesizing it
Molecules that will bind
3
Drug is _
Tested
4
Drug is _
Manufactured
