Developement Of Respiratory System Flashcards

0
Q

When does the lung bud grow downwards & backwards from the oesophagus?

A

The 4th week

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1
Q

What cells line the terminal alveolar sacs?

A

Type 1 alveolar epithelial cells

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2
Q

What’s the other name for lung bud?

A

Respiratory diverticulum

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3
Q

What is of endodermal origin?

A

Epithelia of internal lining of Larynx, trachea, bronchi, lungs

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4
Q

What is of mesothelial origin?

A

Cartilage, muscle & CT of trachea & lungs

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5
Q

What is a fistula?

A

An abnormal connection between 2 structures

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6
Q

What week do the bronchi begin to form?

A

Week 5

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7
Q

Define ‘Atresia’

A

Absence of a normal body passage or cavity

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8
Q

Stenosis

A

Narrowing of passage

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9
Q

When do the Lung buds expand into the body cavity, forming pleura?

A

Weeks 5 & 6

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10
Q

Name the narrow channels either side of the foregut, that are gradually filled by the expanding lungs?

A

Pericardioperitoneal canals

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11
Q

How many tertiary bronchi are in the R & L lung?

A

R = 10

L = 8

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12
Q

Where us the bifurcation of the trachea by birth?

A

At the level of 4th thoracic vertebrae

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13
Q

Name the 4 stages of lung development?

A

Pseudoglandular
Canalicular
Saccular
Alveolar

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14
Q

When is the Pseudoglandular stage?

A

5-16 weeks

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15
Q

When is the Canalicular stage?

A

16-26 weeks

16
Q

When is the Saccular stage?

A

26-term

17
Q

When is the Alveolar stage?

A

> 36 weeks

18
Q

What shape are the cells lining the respiratory bronchioles?

A

Cuboidal

19
Q

What makes up the blood air barrier?

A

Epithelial cells & capillaries

20
Q

What do fetal breathing movements result in before birth?

A

Aspiration of amniotic fluid

Stimulates lung development

21
Q

What produces surfactant?

When do these develop?

A

Type 2 alveolar cells

At the end of the 6th month

22
Q

Define ‘Telectasis’

A

When surfactant remains deposited as a thin phospholipid coat on the alveolar membranes, as fluid is resorbed from alveolar sacs.

23
Q

Oligohydramnios

A

Insufficient amniotic fluid within the lungs.

Causes pulmonary hypoplasia as fluid in lungs stimulates lung growth.

24
Q

Describe the kidneys & feet if babies with oligohydramnios

A

Kidneys are enlarged

Feet are clubbed