Dermatosis of pregnancy

Question 1

Fetal risk

Answer 1

Pemphigoid gastationis
Intrehepatic cholestatis
Pustular psoriasis

Question 2

No fetal risk

Answer 2

Polymorphorphic eruption of pregnancy

Question 3

Pephiogoid gestationis

Answer 3

usually involve umbilicus
plaques studded with vesicles
can be frank bullae
risk correlated to severity of disease
abrupt onset 2-3 trim
can be PP
prone to PP flare
intense pruritis
50% patientsatypical sites
spares face

Question 5

Dx

Answer 5

DIF
Sunmit in michel’s medium
linear C3

Question 6

Pre

Answer 6

Prednisolone 0.5 - 1 mg / day
Reduce dose once improved
Increase to prevent flare at delivery

Question 7

Intrahepatic cholestasis of pregnancy

Answer 7

no primary lesions
all lesions 2 scratching
Rare in Canada
Risk of prem labout
Intrapartum fetal distress
Tends to be 3rd trimester
Can occur 1+2

Answer 8

Intense pruritis

Answer 9

elevation bile acid
Mild increase in LFT

Question 10

Pustular psoriasis of pregnancy

Answer 10

Clustered papules
Once they rupture, leave colarrette of scale
Stats in flexures and spreads peripherally
Triggered by hormonal changes in pregnancy
Risk of placenta insufficiency
Recurrence in subsequent pregnancy common
feel unwell

Question 11

PEP, PUPP

Answer 11

Usually first preg
Usually onset stria
Polymorphous appearance
Occasionally small vesicles.
targetoid
Can be prupuric
Pruritis involved skin
No systemic sx

Answer 12

Histology non specific

Answer 13

REmission within days of delivery
Very itchy - site appropriate topical steroids.
Topical antipruritcs (pramoxine,menthol)
Brief courses of prednisone.

Question 14

atopic eruption of pregnancy

Answer 14

80% no hx atopic dermatitis

Question 15

E type

Question 16

P type