Dermatopathology

Question 1

What is the difference between primary and secondary skin lesions?

Answer 1

Primary lesions develop as a direct result of the disease process
Secondary lesions develop as a consequence of the primary lesion or from the animals actions

Question 2

What is the difference between a papule and a nodule?

Answer 2

a papule is <1cm and a nodule is >1cm

Question 3

What is a wheal?

Answer 3

a discrete area of oedema

Question 4

What size of biopsy punch would you use on the foot pad or nasal planum?

Answer 4

4mm

Question 5

What is a perivascular histopathological pattern?

Answer 5

Inflammatory cells around dermal blood vessels. Very Common.

Question 6

What is an Interstitial histopathological pattern?

Answer 6

Spreading out of inflammatory cells from the original perivascular pattern

Question 7

What is an interface histopathological pattern?

Answer 7

dermo-epidermal junction is obscured by an accumulation of inflammatory cells (lymphocytes)
and/or hydropic degeneration of basal keratinocytes

can indicate autoimmune disease

Question 8

Describe folliculitis

Answer 8

Inflammation of the hair follicle with various parts of the hair follicle involved

Question 9

Describe furunculosis

Answer 9

Inflammatory destruction of the hair follicle with rupture and extrusion of the follicle contents

Generally results in a foreign body response in the dermis

Most commonly seen in biopsies of dogs with deep pyoderma

Question 10

What is a nodular histopathological pattern

Answer 10

Inflammatory cells in dense clusters

Occurs with granulomatous/pyogranulomatous dermatitis