DERMATOLOGY Flashcards

1
Q

Differentiate condyloma lata vs condyloma acuminata.

A

• Condyloma lata = secondary syphilis;

• Condyloma acuminata = Human anogenital warts

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2
Q

Removal of the scale causes pinpoint bleeding called __________ is seen in psoriasis.

A

Auspitz sign

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3
Q

most common infectious complication of varicella

A

Secondary bacterial superinfection of the skin

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4
Q

What agent should not be used for the treatment of psoriasis?

A
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5
Q

What is the most common skin cancer?

A

Basal cell carcinoma (BCC) i

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6
Q

standard of care in managing melanoma

A

Excision biopsy

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7
Q

What is the most aggressive and most common lifethreatening dermatologic disease?

A

Melanoma

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8
Q

What is the most appropriate diagnostic test for SJS?

A

Frozen-section skin biopsy

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9
Q
  • Crusting, ulcerated nodule or erosion.; ill-defined margins
  • Potential for metastasis
A

Squamous Cell CA

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10
Q
A
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11
Q

the development of lesions to the site of an epidermal injury known as ________ is seen in psoriasis.

A

Koebner phenomenon

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12
Q

What is the treatment of choice for severe nodulocystic acne unresponsive to other therapy?

A

Synthetic retinoid isotretinoin

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13
Q

What is the most accurate test for HSV?

A

Viral culture

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14
Q

All patients suspected of Pityriasis rosea should have RPR or VDRL test to rule out syphilis. True or false.

A

true

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15
Q

Condyloma acuminata is seen in ______

A

HPV/ anogenital warts

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16
Q

What is the most serious complication of varicella?

A

Varicella pneumonia

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17
Q

most severe form of SJS

A

TEN

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18
Q
  • Begins with “herald” patch several days or weeks before the rest of the lesions develop. The lesions are erythematous, and salmon colored with fine scale (“cigarette paper”).
  • The lesions on the back appear as a “Christmas tree pattern”
A

PITYRIASIS ROSEA

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19
Q

What is the treatment for localized lesions of psoriasis?

A

Mid-potency Topical steroids

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20
Q

What is the treatment for widespread lesions of psoriasis?

A

ultraviolet light with oral or topical psoralens (PUVA)

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21
Q
  • Multiple violaceous papules on the neck, back, face
  • Associated with Herpes virus, HHV-8
  • Predominant in patients with HIV
  • Effective antiretroviral therapy for HIV infected individuals.
  • Systemic chemotherapy with Adriamycin
A

KAPOSI SARCOMA

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22
Q

What treatment regimen is commonly employed in atopic dermatitis?

A

Low to mid-potency glucocorticoids

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23
Q

What is the most common variety of psoriasis?

A

Plaque-type

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24
Q

What causes the hyperpigmentation in chronic state of stasis dermatitis?

A

Hemosiderin

25
Q

It is an immune-mediated disease, characterized by erythematous, sharply demarcated papules and plaques covered by silvery micaceous scale.

A

Psoriasis

26
Q

What are the ABCDEs of melanoma?

A

o Asymmetric shape

o Border irregularity

o Color variegation (light or dark)

o Diameter >6mm

o Evolving (enlarging, changing or new lesions)

27
Q

_______ are a hallmark of SCC when viewed through a dermatoscope.

A

Dotted or coiled vessels

28
Q

For moderate to severe acne with a prominent inflammation add systemic therapy, such as ________

A

tetracycline or doxycycline

29
Q

What is the drug of choice for mild non-inflammatory acne?

A

Topical retinoids

30
Q

What is the most common of all drug-induced reactions?

A

Morbilliform or maculopapular eruptions

31
Q

The clinical hallmark of acne vulgaris is _____

A

COMEDONE

32
Q

Give examples of drugs that commonly cause SJS or TEN

A

o Sulfonamides

o Allopurinol

o Anticonvulsants

o NSAID (oxicam)

o Lamotrigine

o Nevirapine

33
Q

True or false? Humans are the only known reservoir for VZV.

A

True

34
Q

Hypo/hyperpigmented patches caused by Malassezia furfur

A

Tinea versicolor

35
Q

What is the initial presenting symptom of shingles?

A

pain

36
Q

A 40-year-old woman is recently working as a dishwasher in a newly opened restaurant. Since then, she notices a fluid filled rash forming on her hands that are painful and sometime itchy. On examination, there are deep-seated vesicles on palms and fingers as shown.

A

DYSHIDROTIC ECZEMA

37
Q

Describe the distribution of lesion in scabies.

A

Circle of Hebra

(imaginary circle formed by web spaces of fingers, flexor aspect of the wrist, cubital fossae, anterior axillary folds, nipple area, periumbilical region genital area)

38
Q

What is the most prominent characteristic of atopic dermatitis?

A

Pruritus

39
Q

Herpes labialis can be due to ____

A

HSV-1 or HSV-2

40
Q

Etiologic agent of Seborrheic dermatitis.

A

Pityrosporum ovale

41
Q
  • Central ulceration with pearly, rolled, telangiectatic tumor border.
  • Locally invasive. Rarely metastatic.
  • The nose is the most common site.
  • Remember 3Ps: Papule, pearly, pink
A

Basal cell CA

42
Q

Condyloma lata is seen in ___

A

secondary syphilis

43
Q

Herpes simplex infection of the genital is due to ____

A

HSV-2

44
Q

most severe form of erythema multiforme

A

SJS

45
Q

What is the most debilitating complication of shingles?

A

Pain with acute neuritis and postherpetic neuralgia

46
Q

o <10% TBS area = _____

o 10-30% TBS area = _____

o > 30% TBS area = ______

A

o <10% TBS area = SJS

o 10-30% TBS area = SJS/TEN overlap

o > 30% TBS area = TEN

47
Q

What do you call this condition wherein there is resorption of bones in hands and wrists due to the collapse of the soft tissues in the fingers, a phenomenon sometimes referred to as “telescoping fingers”. This is seen in what disease entity?

A

Arthritis mutilans

Psoriatic arthritis

48
Q

Widespread disease is “crusted” or hyperkeratotic (Norwegian scabies) and responds with ______

A

Ivermectin

49
Q

Syndrome observed in Herpes Zoster characterized as:

o Pain and vesicles in the external auditory canal

o Loss of taste in anterior 2/3 of the tongue

o Ipsilateral facial palsy

A

Ramsay Hunt syndrome

50
Q

What is the pathophysiology of this condition Herpes Zoster/shingles?

A

Reactivation of latent VZV from dorsal root ganglia

51
Q

most important risk factor for basal cell carcinoma

A

Sun exposure

52
Q

What is the pathogenesis of atopic dermatitis?

A

Impaired epidermal barrier

53
Q

What is the most indicated therapy for stasis dermatitis?

A

Leg elevation and compression stockings

54
Q

A 22-year-old man presents with rash on the extensor surface of his elbow and on his gluteal area. On physical examination, there are well demarcated small and large erythematous plaques with adherent silvery scale and the nails reveal the presence of pitting as shown in the images.

A

Psoriasis

55
Q

What the most prevalent of all dermatophytosis?

A

Tinea pedis (Athlete’s foot)

56
Q

What is the best initial test for HSV?

A

Tzanck smear

57
Q

“dewdrops on a rose petal”

A

VARICELLA ZOSTER / CHICKENPOX

58
Q

KOH prep shows “spaghetti and meat-balls” pattern consistent with both hyphae and yeast balls.

A

Tinea versicolor