Dermatology Flashcards
Management of diaper rash
Frequent diaper changes Open air exposure Topical zinc oxide or petroleum jelly 1% hydrocortisone May need topical antibiotics
Perioral dermatitis is most commonly seen in:
Young women - may have history of topical corticosteroid use
Papulopustules on an erythematous base, which may become confluent into plaques with scales. May have satellite lesions. Classically spare the vermillion border
Perioral dermatitis
Management of perioral dermatitis
Topical metronidazole or erythromycin
Oral: tetracycline
Avoid topical corticosteroids!
Most common type of drug reaction/skin eruption
Exanthematous / Morbilliform Rash
Generalized distribution of “bright-red” macules and papules that coalesce to form plaques - typically begins 2-14 days after medication initiation
Drug eruption
Exanthematous/Morbilliform Rash
2nd most common type of drug eruption
Urticaria
3rd most common type of drug eruption
Erythema multiforme
Most common offending drugs with urticaria
Antibiotics and NSAIDs
Management of drug induced exanthematous/morbilliform rash
Oral antihistamines
Management of drug induced urticaria/angioedema
Systemic corticosteroids, antihistamines
Management of drug induced erythema multiforme
Topical steroids, oral antihistamines
Has an increased incidence with Hepatitis C
Lichen planus
The 5 P’s of lichen planus
Purple, polygonal, planar, pruritic papules
Lichen planus most commonly seen on:
Flexor surfaces, skin, mouth, scalp, genitals, nails and mucous membranes
Koebner’s phenomenon
New lesions at site of trauma
Seen in psoriasis and lichen planus
Fine white lines on the skin lesions or on the oral mucosa, nail dystrophy
Wickham Striae
Seen in lichen planus
Management of lichen planus
Topical corticosteroids
Antihistamines for pruritus
Rash will usually spontaneously resolve in 8-12 months
Associated with Human Herpes Virus 7
Pityriasis Rosea
This rash can mimic syphilis, so an RPR should be ordered if the pt is sexually active
Pityriasis Rosea
Solitary solman-colored macule on the trunk, followed by general exanthem 1-2 weeks later
Herald Patch
Pityriasis Rosea
Very pruritic salmon-colored papules with collarette scaling along cleavage lines in a christmas tree pattern
Pityriasis Rosea
Management of pityriasis rosea
None needed PO
Antihistamines, topical corticosteroids as needed.
Can use UVB phototherapy if severe and started early
Most common medications causes SJS and TEN
Allopurinol Sulfonamides Lamotrigine NSAIDs Anticonvulsants
SJS affects _______% of body surface area
< 10%
TEN affects ______% of body surface area
> 30%
Prodrome of fever, malaise, myalgias followed by lesions on face and trunk. Bullous and vesicle formation begins days after
SJS/TEN
Gentle pressure to the skin causes sloughing
Nikolsky Sign
Seen in SJS/TEN
Main cause of death in SJS/TEN
Sepsis and shock secondary to infection
Treatment for SJS/TEN
Admit to hospital, preferably to burn unit
Supportive care is mainstay
Most common cause of erythema multiforme
Secondary to herpes simplex infection
Multiple target-like lesions that spares the mucosa
Erythema Multiforme
Minor
Multiple target-like lesions that includes mucosal involvement
Erythema multiforme
Major
Treatment of erythema multiforme
Typically resolves after 2 weeks
Can give topical steroids and antihistamines