Dermatology Flashcards
terminology primary lesion
flat: macule/ patch: cutaneous color raise: 1. papule/patch 2. vesicles/bulla- fluid filled 3. pustules 4. wheals- cutaneous elevation caused by dermal edema dermal lesion 1) nodule/tumor 2) cyst- nodule with expressible material
secondary lesion
scaling-desquamation of stratum corner crusting-dried exudate pigmentation changes exoriations-linear erosions caused by fingernail scratches scars-thicked fibrotic dermis ulcer-lack of epic/some of dermis atrophy-thinning of epic/dermis fissue-linear crack through dermis
configuation
linear, annular, acuate (semi-circle), grouped, discrete
acral
hands, feet buttock
woods light
pigmentary changes dermatophytes
scraping
fungus-10% KOH exudate hyphae
look for mites eggs feces-scabies
base of vesicle scraped for HSV
hyperkeratosis
need keratolytics like salicylic acid, urea, acids
topical corticosteroid SE
systemic- only if potent and on damaged skin. adrenal suppression,
local SE- more common- w/in days of tx: arena, hirsutism, folliculitis, striae, hyper/hypopigmentation, atrophy, ecchymoses, telangiectasias, tachyphylaxis
antiinflam agents
steroids, tracrolimus ointment (for atopic dermatitis), 1-5% sulfer for acne. tar- eczema, psoriasis
inflammatory D
contact dermatitis, atopic dermatitis, seborrheic dermatitis, pityriasis rosea, psoriasis, miliaria rubra (heat rash)
contact dermatitis
sensitizing agent cause infm of epidermis and superficial dermis
1) allergic contact dermatitis: direct T cell mediated: initial sensitization then rechallenge, not dose dep- poison ivy/oak, jewelry, cream. see: erythematous papule and vesicles. tx- corticosteroid and avoidance
2) primary irritant contact dermatitis: caustic substance irritate skin, dose dep, no sensitization. ex- diaper dermatitis. erythema papules. tx- clean + no moisturizers, change diaper. low potency corticosteroid
seborrheic dermatitis
infant and adolescents. unknown et-maybe hypersensitive to yeast. P: red scales and crusts in area with sebaceous gland= scalp, face, chest, groin. greasy skin lesion
infant- limit to scalp= cradle cap
low potency corticosteroid, ulcer, zine or salicylic acid shampoo, topical anti fungal med
pityriasis rosea
uncommon
psoriasis
3% in kids. 30% first sign in childhood.
etio: if in kid likely auto dom inheritance caused by immune dysregs –> epi prolif
P: scaling papuls, plaques. scalp, nongreasy, hair loss, ears, elbow,. silvery scale. koebner phenomenon- new lesion dev at trauma sites
nail involvement common= pits, distal thickening, lifting of nail med/ destruction
arthritis uncommon in kids
manage- mod-high pot CS, UV light, bit D, 3% salicylic acid, retinoids, anthralin
miliaria rubra (heat rash)
disrupted sweat ducts near upper dermis- occlusion or friction. sweat into skin –> inflm –> more sweat -> more occlusion –> rash
small erythematous pruritic papule or vesicles in rubbed area-inguinal, axilla, chest, neck
tx: no med, avoid occlusive clothes- decr sweating
hypersensitive D
urticaria, serous sickness, erythema multiform, toxic epidermal necrolysis
serum sickness
~urticaria, systemic sign=fever, arthralgia, = organ injury. cause med meds~ cephalosporin
erythema multiform
HS to multi stimuli, drug, viruses etc
EM minor, EM major, steven johnson. all has target lesion= fixed, dull red, oval macule with dusky center containing a papule or vesicle.
toxic epidermal necrolysis
drug rxn. widespread epidermal neurosis, sloughing >30% skin loss.. no target lesion. Nikolsky sign- skin peal with lateral pressure. 10-30% mortality bc sepsis, dehyration, electrolyte abn