Dermatology Flashcards

1
Q

What is porphyria cutanea tarda?

A

Deficiency in the haem-synthetic enzyme URO-D (uroporphyrinogen decarboxylase) in the liver.

This leads to porphyrins which are photoactive (i.e. light activated) and cause oxidative damage to the skin.

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2
Q

What is the most common cause of Tinea capitis? Which population is most affected by this? What is the typical clinical feature?

A

Trichophyton tonsurans (fungus) causing a dermatophyte infection in the scalp.

Occurs mostly in populations of lower socioeconomic status.

Typical feature: scaly circular plaque (ring worm)

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3
Q

Patient has a rash, biopsy reveals septal panniculitis. Diagnosis?

A

Erythema nodosum

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4
Q

Patient has a rash, biopsy reveals intradermal clefting with eosinophils, what might the diagnosis be?

A

Pemphigus

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5
Q

Patient has a rash, biopsy reveals subepidermal bulla with eosinophils, what might the diagnosis be?

A

Bullous pemphigoid

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6
Q

What is Lichen Planus?

How is it treated?

A

Mucocutaneous disorder that affects middle-aged adults with unknown cause, may be drug-induced and associated with Hep C.

May implicate skin, nails or mucous membranes. Cutaneous lichen planus is a pruritic rash with papules +/or plaques with an overlying ‘white lace-like’ pattern (Wickam’s Striae)

Treatment: high potency topical corticosteroids.

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