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Systemic Pathology 2 > Dermatology > Flashcards

Dermatology Flashcards

1
Q

Increased thickness of the stratum spinosum due to hyperplasia or hypertrophy

A

Acanthosis

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2
Q

Loss of hair

A

Alopecia

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3
Q

The process of an individual cell death characterized by rounded, individual brightly eosinophilic keratinocytes

A

apoptosis

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4
Q

A round, eosinophilic cellular extrusion formed by degenerating basal cells dropped off in the lower epidermis or upper dermis

A

Apoptotic body

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5
Q

A hypersensitivity state subject to hereditary influences

A

atopy

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6
Q

Refers to a specific degenerative change in epidermal cells, characterized by swollen, pale, eosinophilic cytoplasm with intracellular edema without vacuolation

A

ballooning degeneration

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7
Q

Abnormal deposits of calcium in tissues as in calcinosis cutis and calcinosis circumscripta

A

Calcinosis

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8
Q

Exaggerated hyperkeratosis in a localized area, especially over pressure points

A

callus

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9
Q

Accumulation of keratin and dried sebum in a dilated pilosebaceous orfices

A

Comedo(-ones)

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10
Q

Dried exudates on the skin surface, composed of secretion +/- epithelial or bacterial debris

A

crust

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11
Q

Refers to some abnormality in cell maturation processes and morphology or the relationship between cells in epithelial structures

A

dysplasia

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12
Q

Loss of normal stratification of the epidermis has the connotation of possible progression to neoplasia

A

Dysplasia

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13
Q

Flat to minimally elevated ring of scale that enlarges peripherally

A

epidermal collarette

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14
Q

separation of the epidermis and dermis with the formation of sub epidermal clefts and blisters

A

Epidermolysis

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15
Q

a rapid development of primary lesions of the skin

A

eruption

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16
Q

redness produced by capillary dilation and congestion

A

eyrthema

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17
Q

superficial linear erosion or ulcer caused by scratching and rubbing

A

excoriation

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18
Q

migration of inflammatory cells and or erythrocytes through the intercellular spaces of the epidermis

A

exocytosis

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19
Q

growing outward from the skin surface

A

exophytic

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20
Q

growing inward from the skin surface

A

endophytic

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21
Q

Deep linear defect from the epidermis to the dermis

A

fissure

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22
Q

inflammation of the hair follicles

A

folliculitis

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23
Q

follicular abscess, “boil,” ruptured folliculitis

A

furnicle

24
Q

thickening of the stratum corner due to an increased number of keratinized cells

A

hyperkeratosis

25
Q

form of hyperkeratosis where the nuclei are lost

A

orthokeratosis

26
Q

type of hyperkeratosis with retention of nuclei in keratinized cells

A

parakeratosis

27
Q

presence of more then normal amount of hair

A

hypertrichosis

28
Q

Thickening of skin with exaggeration of normal markings. consists of acanthuses, hyperkeratosis, and dermal fibrosis

A

lichenification

29
Q

a flat, circumscribed, alteration in skin color or texture. may be pale or hyperpigmented to erythematous

A

macule

30
Q

macule greater than 2 cm in diameter

A

patch

31
Q

circumscribed palpable elevation of skin less than 1 cm in diameter, usually due to cellular infiltration or proliferation, inflammatory or neoplastic

A

papule

32
Q

a large papule >1cm; a circumscribed domed lesion raised above the Lebel of the epidermis- often extends into the dermis

A

nodule

33
Q

Grossly refers to flat-topped papule. microscopically refers to a horizontal dense band-like infiltrate of mononuclear cells in the papillary dermis obscuring the dermo-epidermal junction

A

lichenoid

34
Q

flat topped nodule

A

plaque

35
Q

small circumscribed epidermal or dermal accumulation of purulent exudate

A

pustule

36
Q

purulent dermatitis

A

pyoderma

37
Q

common word for crust

A

scab

38
Q

flake of abnormal or compacted cornfield epidermal cells

A

scale

39
Q

a functional disturbance of sebaceous glands or of lipid metabolism of the epidermis. accompanied by abnormal keratinization processes

A

seborrhea

40
Q

widening of intercellular spaces due to intercellular epidermal edema

A

spongiosis

41
Q

usually, not always, neoplastic nodule

A

tumor

42
Q

a small, circumscribed elevation of epidermis caused by accumulation of clear fluid within or beneath the epidermis

A

vesicle

43
Q

a large intraepidermal or sub epidermal vesicle

A

bulla

44
Q

sharply circumscribed skin elevation produced by edema of the superficial dermis

A

wheal

45
Q

What disease of the epidermis is this?

staphylococcus intermedius
exfoliative toxins
young dogs
pustules

A

Impetigo

46
Q

Which disease of the epidermis is this?

large erythematous macule with peripheral collarettes

exfoliative toxin

staph intermedius

A

Superficial spreading pyoderma

47
Q

Which disease of the epidermis is this?

sub corneal or sub granular vesicles –> pustules

seen on the muzzle, planum nasale, etc

bilaterally symmetrical

not muscocutaneous but often targets face and feet

A

Pempihus foliaceus

48
Q

This vesicular and bulbous disease has a defect with desmocollin 1

A

pempigus folliaceus

49
Q

What type of cells are in the pustule of pempigus folliaceus infected patient?

A

Acantholytic cells

50
Q

Very rare disease of the epidermis that is autoimmune disease, and produces an autoantibody against DG-3

A

Pemphigus vulgaris

51
Q

Which cells is DG-3 strongly expressed by?

A

suprabasilar keratinocytes

52
Q

Which type of vesicular and bulbous disease is seen in the oral cavity and mucocutaneous junctions

A

PV

53
Q

Interface disease of the dermal-epidermal junction that is a relatively common autoimmune disease restricted to the nasal planum for the most part

A

cutaneous lupus erythematous

54
Q

This autoimmune disease has lesions consistent with bilateral depigmentation, erythema, scaling of the planum nasal, and loss of cobble stone appearance of the planum

A

CLE

55
Q

Microscopically, CLE has basal vacuolar degeneration, apoptosis, lichenoid interface lymphocytic inflammation and ______ incontinance

A

pigmentary

56
Q
A

Systemic Pathology 2 (2 decks)

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