Dermatology Flashcards
1
Q
What disorder is Sweet syndrome associated with?
A
AML
Can be malignancy associated (diagnosed before concurrently, after)
Haematological > solid Ca
2
Q
What is the most common drug that causes Sweet syndrome
A
G-CSF
3
Q
What is leukaemia cutis
A
Nodular lesions in those with leukaemia
Not itchy, does not respond to steroids
4
Q
How common is BRAF mutation
A
45% of melanomas BRAF inhibitors (Vemurafenib/Dabrafenib) used for treating metastatic disease. Primary disease - aim for cure with excision
5
Q
Where are mutations in melanoma most likely to be (according to sun exposure)?
A
Intermittent sun exposure - BRAF
Chronic sun exposure - KIT
Acral areas - KIT
Mucosal areas - KIT
6
Q
Side effects of Vemurafinib
A
Squamous cell cancers Arthralgias Rash Fatigue Alopecia Photosensitivity
