DERMATOLOGY Flashcards

1
Q

white patches on tongue, asymptomatic, smoker, T2DM
ix: ?

A

oral leukoplakia
cannot be rubbed off
biopsy
risk of malignancy

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2
Q

exacerbating factors for psoriasis

A

trauma
alcohol
drugs : beta blockers, lithium, NSAIDs, ACEi, infliximab, antimalarials
withdrawal of systemic steroids

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3
Q

tender, erythematous lesions on shin especially
diagnosis ?
pathology ?
causes ?

A

erythema nodosum
inflammation of subcutaneous fat
infections, sarcoidosis, SLE, Behcets, malignancy, lymphoma,
drugs : penicillins, sulphonamides, COCP
pregnancy

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4
Q

intense itchy rash with vesicles on palms of hand, dry skin with peeling and occurs in humid weather like summer,
cause?
treatment ?

A

pompholyx eczema or dyshydrotic eczema
emollients or high potent steroids

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5
Q

palpmoplantar pustulosis - similar to pompholyx eczema - but differs at

A

lesions on other parts of body, have psoriasis and not associated with humid weather

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6
Q

dry, peeling, scaling erythematous skin affecting typically one hand

A

tine magnum

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7
Q

vesicuopustular waxy, yellow brown lesions on palms and soles, associated with reactive arthritis

A

keratoderma blennorhagicum

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8
Q

hypo or. hyper pigmented macule and patches on chest and back, become more noticeable on tanning.
lesions are usually flat
woods light- yellow green fluorescence

caused by ?
first line management ?

A

pityriasis versicolor
malassezia furfur

ketokonazole shampoo

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9
Q

red or silver ring shaped rashes with clear centre, itchy and - usually a isolated lesion

A

tine corporis

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10
Q

photosensitivity and blisters in sun exposed areas, liver and skin disease

A

porphyria cutaenea tarda

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11
Q

circular red rash that spreads outwards from tick bite
systemic symptoms

A

Lyme disease
borrelia burgdorferi

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12
Q

auto immune, well demarcated, erythematous plaques with silvery scales, auto immune related
extensor surfaces

A

psoriasis

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13
Q

orange peel lesions on shins

A

pretibial myxoedema
assoc. with graves disease

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14
Q

small red papule to deep red necrotic ulcers with vioalaceous borders, assc with IBD, connective tissue disease, myeloproliferative
pus- skin - deep ulcers

A

pyoderma gangrenous

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15
Q

shiny plaques on skin, red brown with yellow brown and atrophic centre, erythematous - can have surrounding telangiectasia

plaques- lipid involvement ( yellow brown)- some association with diabetes-

A

necrobiosis lipoidica diabeticorum

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16
Q

fitz Patrick skin types
1
2
3
4
5
6

A
  1. never tans, always burns( red hair, freckles and blue eyes)
    2.usually tans , always burns
    3.always tans, sometimes burns ( dark hair, brown eyes)
  2. always tans, rarely burns
    5.sunburns and tanning after extreme UV exposure ( brown skin- Indian)
  3. black skin - never tans , never burns
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17
Q

papular lesions , hyper pigmented and depressed centrally
present on dorsal surface of extremities

A

granuloma annulare

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18
Q

planus, papular, purple, puristic, polygonal lacy rash
wickhams striae over surface

A

lichen planus
inflammatory condition of skin and mucus membranes

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19
Q

itchy white porcelain spots on the vulva of elderly women
usually are atrophic patches
can be seen in men and in children also

A

lichen sclerosis

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20
Q

self limiting rash , viral in origin, single pink or red oval herald patch and followed by similar lesions on the skin cleavage lines - Christmas tree pattern
itchy only at night time

A

pitryaisis rosea

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21
Q

coin shaped plaques that maybe vesicular or crusted
very itchy

A

Discoid eczema

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22
Q

preceding streptococcal infection , small round oval pink scaly papule - drop/tear shaped

A

guttate psoriasi
- resolves spontaneously
- can try UVB phototherapy

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23
Q

eczema, itchy red rash in pregnancy

A

atopic eruption in pregnancy

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24
Q

third trimester, pruritic rash, appear in abdominal striae
mx ?

A

Polymorphic eruption of pregnancy

emollient or low/mild potent steroids

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25
Q

2-3rd trimester, pruritic blistering rash, peri umbilical later spreading to other parts
mx?

A

pemphigoid gestationitis

oral steroids

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26
Q

eczematous lesions on sebum rich areas- eyebrows, nasolabial folds, peri auricular and periorbital
associated with HIV , Parkinson’s

mx?

A

seborrheic dermatitis
- caused by malasezzia

ketoconazole shampoo
topical steroid

27
Q

itchy, vesicular skin lesions on extensor surfaces
associated with coeliac, IBD
skin biopsy - igA deposits

A

dermatitis herpetiformis

  • gluten free diet
  • dapsone
28
Q

rapidly progressive from small lesions to raised red brown lesion, often spherical in shape, smooth surface
may bleed or ulcerate
linked to trauma, pregnancy

A

pyogenic granuloma

29
Q

infectious disease, contamination from infected animals- parapoxvirus
single or few lesions on hands and fingers with surrounding erythema and regional lymphadenopathy

A

ORF

30
Q

contagious, crusted golden lesions typically around the mouth
diagnosis ?
caused by ?
first line ?
second line ?
if extensive

A

impetigo
stepto/staph
hydrogen peroxide – if doesn’t help then topical fusidic acid

flucloxacillin, if pen allergic then erythromycin

31
Q

blisters, pruritic- no mucosal involvement

A

bullous pemphigoid

mx- biopsy, oral steroids

32
Q

blisters with mucosal involvement

A

pemphigus vulgaris

33
Q

blisters or bullae in response to trauma to fragile skin
usually manifests early in childhood

A

epidermolysis bullae

34
Q

sweets syndrome associated with

aka :

A

acute myeloid leukaemia

acute febrile neutrophilic dermatosis

35
Q

skin disorders associated with diabetes

A

necrobiosis lipidoica
vitiligo
lipoatrophy
candidiasis
granuloma annulare

36
Q

children, multiple raised pearly white/flesh coloured lesions with central umbilication/dimple

A

molluscum contagious

self limiting, referral if associated to HIV, lesions near eye or genital area

37
Q

acne rosacea— redness, telangiectasia rx:

acne vulgaris - pustules, comedones rx:

A

– alpha agonist brimonidine to reduce flushing, topical ivermectin , metronidazole/azelaic acid
laser for telangiectasia

– topical steroid/antibiotics

38
Q
A
39
Q

venous ulcer
ix:
mx:

A

ABPI

compression stockings, oral pentoxyifylline - vasodilator

40
Q

hirsutism - androgen dependent hair growth causes

A

PCOS,
cushings syndrome
adrenal hyperplasia
androgen therapy
obesity
adrenal tumour
androgen secreting tumours
phenytoin, steroids

rx- oral COCP - co-cyprindiol, or eythnylestradiol, and drosperinone
topical eflornithine

41
Q

hypertrichosis causes

A

minoxidil, ciclosporin, diazoxide
congenital
porphyria cutanea tarda
anorexia nervosa

42
Q

contact dermatitis - late type 4 hypersensivity

A

skin patch test -

43
Q

target lesions on hands, feet and spreading to torso- mild pruritic,
self limiting
triggered by infections ( mycoplasma or HSV), drugs ( penicillins, allopurinol, NSAIDS, OCP,), SLE, sarcoidosis, malignancy

A

erythema multiforme

44
Q

on pressing down go white and fill from
centre ?
edges ?

A

spider nave

heridetery hemorrhagic telangiectasia

45
Q

first line treatment for capillary hemagioma

A

propranolol

46
Q

isotretinoin should not be combined with tetracyclines due to risk of ?

A

intracranial hypertension

47
Q

sun exposed areas, nodule with a central depression, some telangiectasia,

A

BCC

48
Q

sun exposed areas, ass with actinic keratosis, can appear as an ulcer but no rolled edges

A

SCC

49
Q

acne vulgars treatment of choice in pregancy

A

erythromycin

50
Q

acne vulgaris treaments to avoid in pregnancy

A

doxy/lymecycline
steroids

51
Q

painful lesion on the helix of ear

A

chondrodermatitis nodularis helices

rx: cyrotheraphy, steroid, collagen injection, surgery

52
Q

scabies
1) type of hypersensivity
2) itching persists how many weeks post treatment
3) treatment

A
  1. type 4 delayed
  2. 6 weeks , retreat if new burrows
  3. permetrin 5%v- leave on skin for 8-12hrs or malathion 0.5% leave on skin for 24hr
    repeat in 7 days

severe infection with crusting skin - IVERMECTIN

53
Q

auspitz sign

A

erythematous plaques covered in silver white scale when scraped expose the underlying red membrane that bleeds- seen in psoriatic plaques

54
Q

struck on appearance on skin, varying colours, keratin plugs can be seen in older people

A

seborrheic keratoses
rx- curettage, shave biopsy, cryosurgery

55
Q

bowens disease

A

squamous cell carcinoma insitu

56
Q

familial history, atypical multiple mole-melanoma, variable size color and irregular borders

A

dysplastic naevus syndrome

57
Q

recurrent MTP joint pain, peptic ulcer disease and ruddy complexion
cause for pruritic ?

A

polycythemia

58
Q

depigmented skin patches, associated with auto immune conditions ( alopecia aerate, hashimotos, pernicious anemia, SLE, T1DM, Addisons)
dx:
tx:

A

vitiligo

topical steroids/ tacrolimus

59
Q

well demarcated, erythematous circular patch with raised edges and central hypopigmentation with itch

A

tinea corporis
caused by trichophyton

60
Q

skin lesion associated with rheumatic fever, annular erythematous macules or papule that spread outwards with central clearance

A

erythema marginatum

61
Q

nose bleeds, IDA, erythematous lesions on skin, mucus membranes

A

heridetary hermorrhagic telangectasia

aka osler weber rendeu syndrome

62
Q

first line in treatment of acne rosea

A

topical ivermectin

other alternatives- topical azelaic acid and metronidazole

63
Q

lower limb lesions, pink/brown well defines, dimple sign - on pressing
asymptomatic

A

dermatofibroma

64
Q
A