Dermatology

Question 1

What is Koebner phenomenan?

Answer 1

Psoriatic skin lesion develops at a site where skin was previously injured

Usually linear lesions

Question 2

State some drugs that can cause psoriasis

Answer 2

β-Blocker
Lithium
Anti-malarial (chloroquine and hydroxychloroquine)
NSAIDs
ACEi
Infliximab
Steroid withdrawal

Question 3

What is a fatal form of psoriasis? What is it associated with?

Answer 3

Generalised pustular psoriasis
Triggered by sudden withdrawal of steroid Rx
Associated with hypoparathyroidism

(Erythrodermic psoriasis also fatal)

Question 4

What is Auspitz phenomenon?

Answer 4

Pinpoint bleeding with removing scales

Question 5

Which anti-TB medication can cause pellagra?

Answer 5

Isoniazid

Question 6

What is a rare but important side effect to be aware of for penicillins?

Answer 6

Toxic epidermal necrolysis

Question 7

What drugs can induce TEN?

Answer 7

phenytoin
sulphonamides
allopurinol
penicillins
carbamazepine
NSAIDs

Question 8

What oral antibiotics can be used in severe cases of acne rosacea?

Answer 8

doxycycline or oxytetracycline or azithromycin

In mild cases –> metronidazole