Dermatology Flashcards
IgG deposition at the dermo-epidermal junction
bullous pemphigoid
Bullous pemphigoid vs pemphigus vulgaris
Oral lesions more common in pemphigus
Intercellular deposition of IgG
pemphigus vulgaris
symmetrical reticulated, violaceous patches
Livedo reticularis
Due to dilation of capillaries
Idiopathic
Or 2 SLE, malignancy, vasculitis, cholesterol emboli
ASOT test for
Streptococcus throat
target lesions
Dx?
a/w which drugs?
erythema multiforme
ABx
penicillins
sulphonamides
isoniazid, tetracycline
AEDs
phenytoin, carbamazepine, phenobarbitone
Other
Aspirin, NSAIDs, radiation, pregnancy
erythema multiforme
a/w which viruses?
viruses - herpes simplex 1 and 2, hepatitis B, Epstein-Barr virus (EBV), enteroviruses
small agents - Mycoplasma pneumoniae
bacteria - Group A Streptococcus, eosina, and
other - Mycobacterium tuberculosis, histoplasma, coccidioides.
Hydroxychloroquine
Indication?
Screen for before starting?
Malaria
Eye toxicity so see ophthalmologist and regular f/up whilst on it
indurated plaques on cheeks
the scarring alopecia hyperkeratosis over the hair follicles.
Discoid lupus
dermal papules
lesions become larger, annular plaques
on extensors
NOT ITCHY
granuloma annulare
benign inflammatory condition
aetiology unknown
(nb. psoriasis is silvery plaques + itchy)
itchy, shiny
violaceous papules
often on extremities
White patch/ ulcer BUCCAL MUCOSA
nail deformity, scarring alopecia
Dx?
Associated with which virus?
Lichen planus
Hep C increases susceptibility
pruritic vesicles
elbows, knees, and buttocks
not responded to topical steroids
dermatitis herpetiformis
intensely itchy, red, scaling rash which affects his scalp predominantly
patch on chest and beard
Dx?
Rx?
seborrhoeic dermatitis
ketoconazole shampoo
On cyclosporin
New hard round lesion on face
Dx?
SCC
Immunosuppression -> SCC and BCC
NB melanoma normally irrgular, pigmented, growing mole +/- bleeding
Strep throat 2 weeks ago
Abx for 1 week
now multiple erythematous papules + plaques on trunk and UL with superficial scaling
Dx?
Guttate psoriasis
classically seen two to three weeks after streptococcal infection, and usually resolves spontaneously
Starting Dapsone
what do you check for?
G6PD deficiency
absolute CI to dapsone as it can lead to severe haemolytic anaemia
Starting cyclosporin
what do you monitor?
BP
can get HTN
Condition exacerbated by exposure to light?
acute intermittent porphyria
pellagra
acne vulgaris
Pellagra
fragility of sun exposed skin
after mechanical trauma
leading to erosions and bullae
worst on dorsal hands, forearms and face
porphyria cutanea tarda
1 week after amoxicillin for UTI
Haematuria
AKI
fever
widespread erythematous rash
Eosinophilia
interstitial nephritis
40-60% of cases due to drug hypersensitivity
Typically B lactam or NSAID
can get liver involvement
Rx = stop drug +/- high dose Pred
whitish discolouration up to nail bed of both feet
dermatophyte infection confirmed
Rx?
Terbinafine
first line treatment for fungal nail infection (onychomycosis)
generalised erythema and pustule formation
BG psoriasis
Dx?
erythroderma
emergency
admit to hospital
Dermatitis herpetiformis associated with?
coeliac disease
intensely pruritic vesicles
elbows, knees, buttocks, and scalp
not usually responsive to topical steroids
DH
Give Dapsone (check for G6PD before)
itching and blistering of the hands and the forehead
excoriation marks on back of hands
Dx?
Porphyria cutanea tarda
