Dermatological Emergencies Flashcards
Necrotising fasciitis progression
Painful erythema
Few days later - skin breakdown
Later - Anaesthesia + blue/grey necrosis
Hypotension + Fever
Types of necrotising faciitis
Type I
Type II
Type I necrotising faciitis
Polymicrobial
Mix of aerobic and anaerobic pathogens
Type II necrotising faciitis
Monomicrobial:
Staph Aureus - most common
GAS
Mx of necrotising faciitis
Urgents surgical referral Debridement Broad spectrum IV abx Haemodynamic support Amputation
Abx for necrotising faciitis
Carbapenam or beta lactamase inhibitor bacteria
+ Clindamycin
+ MRSA cover (Vancomycin)
When to think about necrotising faciitis
Disproportional painful erythema
Erythema with purple/grey tinge
Systemically unwell
Other name of meningococcaemia
Meningococcal septicaemia
RFs for Meningococcal septicaemia
Immunocompromised
Asplenic
Sx of Meningococcal septicaemia
Fever Non blanching rash Headache N/V Neck stiffness Photophobia Seizure
Rx of Meningococcal septicaemia
Ceftriaxone IV 7 days
Close contact prophylaxis for Meningococcal septicaemia
Rifampicin
Complications of Meningococcal septicaemia
Seizures
DIC
Raised ICP
Scale of Stevens-Johnson syndrome
Erythema multiforme
Stevens-Johnson syndrome - mucus membrane involvement
Toxic Epidermal Necrolysis
Sx of Stevens-Johnson syndrome
Flu like Sx
Few days later - target rash non itchy
Burning/peeling of skin
Ulcers - genital tract, mouth/throat, corneal
Complications of Stevens-Johnson syndrome
Death
Blindness
Skin scarring
Secondary cellulitis
Mx of Stevens-Johnson syndrome
Stop causative medication / abx for infection
Moisturiser
Fluids
Corticosteroids - skin inflammation
Medication causes of Stevens-Johnson syndrome
Allopurinol
Carbemazepine
Lamotrigine
Cotrimoxazole
Viral causes of Stevens-Johnson syndrome
Mumps
HSV
EBV
Coxsackie virus
RFs for Stevens-Johnson syndrome
Immunosuppression
Previous Stevens-Johnson syndrome
FHx of Stevens-Johnson syndrome
Prognosis of Stevens-Johnson syndrome
Skin grows back depending on severity
Weeks to months
Erysipelas
Distinct superficial cellulitis of face
Eczema Herpeticum Sx
Punched out blisters Painful Clusters Systemically unwell Lymphadenopathy
Causes of Eczema Herpeticum
HSV
HSV 1 most common