Dermatological Descriptions (Lec 1) Flashcards
Skin Structure
(4 Layers)
- Epidermis
- Basement Membrane - velcro to hold layers together
- Stratum Basale - absorb UV radiation to protect from environment
- Dermis - vital structures
- SQ

Skin Functions
(10)
- Protects from environment
- Absorbs harmful UV radiation
- Resists mechanical shock
- Mediates sensation
- Thermoregulation
- Regulates body fluid loss
- Assists bc toxin excretion
- Assists in Vit D synthesis
- 10-15% vit D prdn from sun
- Rest from GI
- Immunologic barrier to pathogenic organisms
- Langerhan’s cells - WBC in dermis that recognize foreign substances and start a cascade
- Affects social/sexual communication
- Never trivialize this!!
Morphology of Skin Lesions
(6)
- Color and descriptive terms
- Primary skin lesions
- Secondary skin lesions
- Special skin lesions
- Arrangement
- Distribution
Report each of these c every dermatologic finding
Dermatologic Finding Reporting Template
(5)
- Size
- Color and descriptive terms
- Type of primary, secondary, or special skin lesion
- Arrangement
- Distribution
Dermatologic Colors and Descriptive Terms
(6)
- Depigmented
- Hypopigmented → Hyperpigmented
- Erythematous → Violaceous
- Atrophic → Lichenified
- Verrucous
- Umbillicated
Depigmented
(template category, definition)
Template Category: Color/descriptive terms
Definition: Absence of melanocytes, therefore no skin color

Hypopigmented
(template category, definition, comparative term)
Template Category: Color/descriptive
Definition:
- Decreased # of melanocytes but decreased prdcn of melanin
- Lighter than skin color
- Appears in healing stages of some rashes
Comparative: Hyperpigmented

Hyerpigmented
(template category, def, comparative term)
Template: color and descriptive term
Def:
- normal # of melanocytes but inc melanin prdcn
- darker than normal skin
- often d/t scratching c comorbidity
- heals c creams
Comparative term: hypopigmented
Erythematous
(template category, def)
Category: color and descriptive terms
Def: redness

Atrophic
(template category, definition, comparative term)
Category: color and descriptive terms
Def: skin thinning
- epidermal - “cigarette paper” wrinkling
- dermal/SQ - palpable skin depression
Comparative: lichenified

Lichenified
(template category, def, comparative term)
Category: color and descriptive terms
Def:
- focal area of thick skin
- produced by chronic manipulation (like itching)
- accenutated skin warts - “washboard”
Comparative: atrophic

Verrucous
(template category, def)
Category: color and descriptive terms
Def: hyperkeratotic or wart-like

Umbilicated
(template category, def)
Category: color and descriptive terms
Def: central “belly button”-like depression

Primary Skin Lesion
(def, 6 descriptive categories)
Def: initial lesions, not alrtered by trauma (including itching) , manipulation, or natural regression over time
Terms:
- Macule → Patch
- Papule → Plaque
- Nodule
- Pustule → Cyst
- Vesicle → Bullae
- Wheal
Macule
(template category, def, comparative term)
Category: primary skin lesions
Def: small (<5mm), flat, circumscribed skin discoloration. lacks surfacce elvation or depression.
Comparative Term: patch

Patch
(template category, def, comparative term)
Template: primary skin lesion
Def: large (>5mm), flat circumscribed skin discoloration. lacking surface elevation or depression
Comparative: macule

Papule
(template category, def, comparative term)
Category: primary skin lesion
Def: <5 mm elevated solid lesion
Comparative: plaque

Plaque
(template category, def, compartive term)
Category: primary skin lesion
Def: >5mm elevated solid confluence of papules, lacks a deep component
Comparative: papule

Nodule
(template category, def)
Category: primary skin lesion
Def: >5mm elevated, solid, deep lesion
Comparative: nodule, papule

Pustule
(template category, def, comparative term)
Category: primary lesion
Def: papule (<5mm) containing purulent material
Comparative: cyst
Note: these do not always indicate infection. ex - psoriasis is simply an immune response. cultures will be negative

Cyst
(template category, def, comparative term)
Category: primary skin lesion
Def: nodule (>5mm) containing fluid or semisolid material
Comparative: pustule

Vesicle
(template category, def, comparative term)
Category: primary skin lesion
Def: Papule (<5mm) that contains clear fluid
- If filled c blood, “hemorrhagic vesicle”
Comparative: bullae

Bulla
(template cateogry, def, comparative term)
Category: primary skin lesion
Def: >5mm localized fluid collection
- if filled c blood, “hemorrhagic bulla”
Comparative: vesicle

Wheal
(template category, def)
Category: Primary skin lesion
Def: firm, edematous plaque that is evanescent and pruritis
Note**: iatrogenic creation c PPD, local anesthesia, etc

Secondary Skin Lesions
(definition, list 4 tyes)
Def: skin characteristics created by trauma (including itching), infection, manipulation, or normal time-related developments
Types:
- Scale → Crust
- Erosion → Ulcer
- Fissure → Excoriation
- Scar
Scale
(template category, def, comparative term)
Category: secondary skin lesion
Def: thickened stratum corneum, secondary to keratinocyte hyperproliferation
- hyperproliferation evident on microscopy
Comparative: crust

Crust
(template category, def, comparative term)
Category: secondary skin lesion
Def: collection of cellular debris
- scab = dried serum, blood
Comparative: scale

Erosion
(template category, def, comparative term)
Category: secondary skin lesion
Def: superficial focal loss of epidermis that heals s scarring
- no scars b/c no collagen superficial to dermis
Comparative: ulcer

Ulcer
(template category, def, comparative term)
Category: secondary skin lesion
Def: full thickness focal loss of epidermis and dermis, heals c scarring
- *scar d/t collagen disturbance in dermis *
Comparative: erosion
Fissure
(template category, def, comparative term)
Category: secondary skin lesion
Def: verticle loss of epidermis and dermis. sharply defined walls
- ie - “cracked” skin
Comparative: excoriation

Excoriation
(template category, def, comparative term)
Category: secondary skin lesion
Def: linear erosion induced by scratching
Comparative: fissure

Scar
(template category, def, two types)
Category: secondary skin lesion
Def: collection of new CT that implies dermoepidermal damage
Types:
- hypertrophic - too much collagen conserved. scar heals “too well”
- atrophic - striae-like depression

Special Skin Lesions
(list 6 types)
- Telangiectasia
- Petechiae → Purpura
- Comedone
- Target lesion
- Burrow
- Striae
Telangiectasia
(template category, def)
Category: special skin lesion
Def: small, dilated, superficial, blanchable BV
Note**:
- means “tiny angiomas,” “broken capillaries”
- detected c dioscopy

Petechiae
(template category, def, comparable term)
Category: special skin lesion
Def: < 5mm extravasation of RBC into dermis, nonblanchable
Comparable: pupura

Pupura
(template category, def, comparative term)
Category: special skin lesion
Def: >5mm extravasation of RBC into dermis, nonblanchable
Comparative: petechiae
Note: violacious purpura = bruise

Comedone
(template category, def, two types)
Category: special skin lesion
Def: folliculocentric collection of sebum and keratin
Types:
- Closed = “whitehead,” unoxidized and hard to pop s cutting skin
- Open = “blackhead,” oxidized and easy to pop

Target Lesion
(template category, def)
Category: special skin lesion
Def: three-zoned lesion
- center bull’s eye
- second pale zone
- third erythematous ring

Striae
(template category, def, 3 causes)
Category: Striae
Def: irreversible atrophic violaceous linear damage to skin
Causes:
- Topical steroids (never give unlimited steroid refills! follow up c steroid pts to make sure they are not applying them to pigmentation)
- Cushing’s syndrome
- Excessive rapid growth

Burrows
(template category, def)
Category: special skin lesion
Def: elevated channel in the superficial epidermis, produced by parasites (scabies, hookworm)
Note**: exist b/c parasites cannot burrow thru dermis so they tunnel around epidermis trying to find the blood-richest areas

Characteristic Arrangements
(list 6)
- Annular
- Gyrate
- Dermatomal
- Linear
- Grouped
- Koebernization
Annular
(template category, def)
Category: characteristic arrangement
Def: ring-shaped

Gyrate
(template category, def)
Category: characteristic arrangement
Def: from Latin, “to turn in a circle”
brain-like

Dermatomal
(template category, def)
Category: characteristic arrangment
Def: follows neurocutaneous dermatomes

Linear
(template category, def)
Category: characteristic arrangement
Def: skin lesions in a linear configuration

Grouped
(template category, def)
Category: characteristic arrangement
Def: skin lesions in a grouped configuration…

Koebnerization
(template category, def)
Category: characteristic arrangement
Def: traumatized skin produces lesions. this phenomenon (Koebner Phenomenon) only occurs c certain skin lesions
- lichen planus
- LN (pediatric dz)
- psoriasis
Note**: trauma may be a burn, including sunburn

Distribution
(significance, three types)
Significance: certain dermatologic conditions have specific distribution patterns, so it is vital to describe that when discussing a finding
Types:
- Bilateral/unilateral
- Flexural/extensor
- Malar