Dermatologic Drugs

Question 1

Isotretinoin

Functional Classification

Answer 1

Antiacne agent, retinoid

Question 2

Isotretinoin

Contraindications

Answer 2

Hypersensitivity, inflamed skin

Pregnancy (X)

Question 3

Lindane

Functional Classification

Answer 3

Scabicide, pediculicide

Question 4

Lindane

Chemical Classification

Answer 4

Chlorinated hydrocarbon (synthetic)

Question 5

Lindane

Mechanism of Action

Answer 5

Stimulates nervous system of arthropods, resulting in seizures, death

Question 6

Lindane

Uses

Answer 6

Scabies, lice (head/pubic/body), nits in those intolerant to or who do not respond to other agents

Question 7

Lindane

Contraindications

Answer 7

Hypersensitivity, patients with known seizure disorders, Norwegian (crusted) scabies
Premature neonate; inflammation of skin, abrasions, skin breaks; seizure disorder

Question 8

Lindane

Side Effects

Answer 8

CNS: tremors, SEIZURES, CNS TOXICITY, stimulation, dizziness (Chronic inhalation of vapors), anxiety, insomnia
CV: VENTRICULAR FIBRILLATION (chronic inhalation of vapors)
GI: Nausea, Vomiting, Diarrhea, liver damage (inhalation of vapors)
GU: KIDNEY DAMAGE (chronic inhalation of vapors)
HEMA: APLASTIC ANEMIA (chronic inhalation of vapors), MYELOSUPPRESSION
INTEG: Pruritus, Rash, Irritation, Contact Dermatitis

Question 9

Lindane

Nursing Considerations

Answer 9

ASSESS:

• Skin for abrasions, breaks, inflammation; don not use on these areas
• INFESTATION: head, hair for lice, nits before and after treatment; if scabies present, check all skin surfaces; identify source of infection: school, family, sexual contacts

PERFORM/PROVIDE:

• Isolation until areas on skin, scalp have cleared, treatment completed
• Removal of nits with fine-toothed comb rinsed in vinegar after treatment; use gloves

Question 10

Isotretinoin

Uses

Answer 10

Severe recalcitrant nodulocystic acne