Dermatitis Herpatiformis

Question 1

What is the eponymn associated with DH?

Answer 1

Duhring disease

Question 2

True or false: in women with DH, flares often coincide with the menstrual cycle.

Answer 2

True

Question 3

True or false: most patients with DH have symptoms consistent with a gluten-sensitivity enteropathy.

Answer 3

False; although 70-100% of patients with DH will have histologic abnormalities of the jejunal mucosa, most patients are asymptomatic

Question 4

What systemic drug is most commonly used to treat DH? What is the other mainstay of therapy?

Answer 4

• Dapsone
• A gluten-free diet; the majority of patients who adhere to a strick gluten-free diet can eventually stop their dapsone

Question 5

What HLA type is associated with DH?

Answer 5

HLA-B8

HLA-DR3 and DQw2 have also been associated

Question 6

True or false: a gluten-free diet decreases the incidence of intestinal lymphoma associated with gluten sensitivity enteropathy.

Answer 6

True