Dermatitis atopica Flashcards

1
Q

Por que la barrea cutanea esta alterada?

A

Filgrina

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2
Q

Que hacen las proteasas con lso cornocitos

A

desasdhesion

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3
Q

Fisiopatologia de el deteriro de la membrana

A

Deficiencia de filagrina
Aumento de proteasas
Lipidos anomalos

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4
Q

Desregulacion. inmunitaria en la que estan involucradas las interleucinas

A

Adaptativa

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5
Q

Principales interleucinas afectadas

A

4 y 13

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6
Q

Interleucina que causa muchi prurito

A

Interleucina 4

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7
Q

Que Th esta en respuesta aguda

A

TH2

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8
Q

Cual es la desregulacion inmunitaria con celulas linfaticas

A

Innata

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9
Q

Th en desregulacion inmunitaria cronica adaptativa

A

Th1, Th17 y Th22

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10
Q

Principal factor de riesgo

A

Deficiencia de filagrina

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11
Q

Gen involugrado en deficiencia de filagrina

A

FLG

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12
Q

Fase en la que hay mayor predominio de citocinas TH2

A

Agudas

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13
Q

Que estadio es una placa eritematosa y edematosa con vesiculacion, exudacion y costra serosa

A

Aguda

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14
Q

Que estadio es una lesion eccematosa con eritema, descamacion y formacion de costra variable

A

Subaguda

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15
Q

Que estadio es una leson placa engrosada con liquenizacion y descamacion

A

Cronicas

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16
Q

DA menores de 2 años

A

LACTANTE

17
Q

Edad en DA infantil

A

2-12 años

18
Q

Como se led enomina al eccema de los labios

A

Quelitis seca

19
Q

Que se vera en la biopsia

A

Paraqueratosis (nucleos en el estrato corneo) y edema (espongiosis)