DERMATITIS Flashcards

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1
Q

Name the 7 classifications of dermatitis

A
Contact allergic
Contact irritant
Atopic
Drug-induced
Photosensitive
Lichen simplex
Stasis dermatitis
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2
Q

What is the basic pathogenesis behind contact allergic dermatitis?

A

Type 4 (delayed) hypersensitivity

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3
Q

What is the basic pathogenesis behind lichen simplex dermatitis?

A

Physical trauma to skin, e.g. persistent scratching

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4
Q

List some common causes of contact allergic dermatitis

A

Nickel
Latex
Topical therapies
Plants

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5
Q

What investigation can be used to identify substances causing contact allergic dermatitis?

A

Patch testing

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6
Q

What is involved in patch testing?

A

Wells containing allergen applied to skin on back and left for 48-96hrs

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7
Q

Which dermatitis - contact allergic or irritant - is a non-specific reaction?

A

Contact irritant dermatitis

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8
Q

List examples of things that cause contact irritant dermatitis

A

Soap
Detergent
Oil
Nappy rash

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9
Q

Contact allergic and irritant dermatitis are easy to distinguish. True/False?

A

False

Often need to patch test

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10
Q

List some symptoms and signs of atopic dermatitis

A
Pruritis
Scaling
Poorly defined erythema
Dry skin
Flexural distribution
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11
Q

Secondary infection of atopic eczema is common and occurs due to which organism?

A

Staph aureus

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12
Q

Which virus causes eczema herpeticum?

A

Herpes simplex virus

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13
Q

What does eczema herpeticum look like? (buzzword!)

A

Monomorphic, punched-out lesions

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14
Q

What is the UK diagnostic criteria for atopic eczema?

A
Itch + at least 3 of:
Flexural rash
History of atopy
Dry skin
Onset before the age of 2
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15
Q

List step up therapy for eczema

A

Emollients + topical steroid;
if infection add antibiotics;
phototherapy;
immunosuppressants if systemic upset

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16
Q

What is the most important gene related to atopic eczema?

A

Filaggrin