Derm2 Flashcards

1
Q

Name 3 examples of emollients

A

White soft paraffin and liquid paraffin
Aqueous cream
Emulsifying ointment

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2
Q

How much topical steroid do you use?

A

A finger tip unit (length of finger) for the area of 2 hands

30g tube is enough to cover whole body once

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3
Q

5 local SE to topical steroid cream

A
Skin atrophy
Striae
Telangiectasia
May mask/exacerbate skin infections
Acne
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4
Q

Name 7 systemic SE to steroids

A
Cushing's
Immunosuppression
Hypertension
Diabetes
Osteoporosis
Cataracts
Steroid induced psychosis
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5
Q

Name 2 sedating and 2 non sedating antihistamines

A
Sedating (chlorpromazine, hydroxyzine)
Non sedating (cetirizine, loratidine)
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6
Q

Unwanted effects of older antihistamines

A

Sedation

Anticholinergic (dry mouth, urinary retention)

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7
Q

Name 2 topical antibiotics

A

Fusidic acid

Mupirocin (bactroban)

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8
Q

Name 2 antiseptics

A

Chlorhexidine

Povidone-iodine

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9
Q

Name an oral retinoid

A

isotretinoin

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10
Q

What are retinoids used for?

A

Acne
Psoriasis
Disorders of keratinisation

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11
Q

SE of retinoids

A

Teratogenicity
Dry skin, eyes
Disordered liver function
Lipid profile

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12
Q

Give 2 tips for topical steroids

A

Only for short term use (up to 2 weeks)

Only use 1% hydrocortisone for face

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13
Q

Where are skin scrapes taken from?

A
Scaly lesions (suspected fungal infection)
Burrows in scabies)
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14
Q

How do you do an ABPI?

A

BP at dorsalis pedis/posterior tibial
BP at brachial artery
Ratio, normally >0.8

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15
Q

What do you never prescribe in psoriasis?

A

Oral steroids

Beta blockers

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16
Q

What is scleroderma?

A
Fibrotic change
Probably autoimmune
Can affects joints (contractures)
Decreased blood supply-> ulcers
Can lead to systemic sclerosis
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17
Q

8 causes of ulcers

A
Venous
Arterial
Vasculitis
Neuropathic
Infectious (TB, protazoa, herpes)
SCC
Drug induced (nicorandil, methotrexate)
18
Q

Steps towards skin cancer

A

Acitinic keratoses
Bowen’s
SCC

19
Q

What does Bowen’s look like?

A
Can look like patches of psoriasis
Inflammatory base
Disordered structure
Keratinisation
Fairly well defined border
Tiny regular clods of blood vessels
20
Q

Treatment of rosacea

A

Topical ivamectin/metronidazole

Oral antibiotics

21
Q

What is an epidermoid cyst?

A

Normal epidermis contained under skin
Produces skin
Can get infected and cause an abscess

22
Q

What is Breslow thickness?

A

> 1mm thickness of melanoma is likely to have spread

Other factors: mitotic rate, poorly differentiated

23
Q

Describe the progress of a mole

A

If acquired, it progresses from a junctional nevus (most common in children) to a compound nevus and eventually to an intradermal nevus

24
Q

What are the 6Ps of lichen planus?

A

Pruritic, purple, polygonal, planar papules and plaques

25
Q

Difference between varicella zoster and herpes zoster?

A

Varicella: chickenpox
Herpes: shingles

26
Q

What is erysipelas?

What is cellulitis?

A

Erysipelas involves the superficial dermis
and epidermis, often resulting in superficial
blistering. Lymphangitis is common.
Cellulitis involves the deep dermis and
subcutaneous tissue.

27
Q

Function of langerhan cells

A

Antigen presenting cells

28
Q

What cells are involved in wound healing?

A

Neutrophils and macrophages phagocytose cellular debris and invading bacteria
Fibroblasts form granulation tissue
Epidermal cells proliferate and migrate (re-epithelialisation)

29
Q

Difference between Steven Johnson and TEN

A

SJ is mucosal, infection or drug induced

TEN is skin and mucosa, systemic toxicity, full thickness epidermal necrosis

30
Q

How can you tell it’s erysipelas?

A

Inflammation
Fever, malaise, rigors
Well-defined red raised border

31
Q

Which antibiotics are used to treat Staph Scalded Skin Syndrome?

A

Fusidic acid
Best lactamase resistance penicillin
Erythromycin
Cephalosporin

32
Q

Define tinea unguium

A

fungal tinea infection of the nail

Yellow, crumbly, thickened

33
Q

Define pityriasis versicolor

A

Scaly fungal pale brown patches that fail to tan

usually asymptomatic

34
Q

What is imiquimod cream used for?

A

Anogenital ulcers
Actinic Keratosis
Bowen’s
BCC

35
Q

3 types of melanoma and associations

A
Nodular (young and middle aged, intermittent high intensity Uv exposure) 
Lentigo maligna (elderly, face, cumulative UV)
Acral (dark skinned, palms soles and nail beds, elderly)
36
Q

Genetic defect for eczema?

A

Fillagrin protein function

Skin barrier defect

37
Q

Name a topical immuno modulator

A

Tacrolimus

38
Q

Name the bacteria that causes acne

A

Proprionibacterium acnes

39
Q

Name 7 most common causes of blisters

A
Impetigo 
Herpes (zoster/simplex)
Pompholyx eczema
Contact dermatitis 
Burns
Insect bites
40
Q

what features are associated with venous ulcers?

A

warm skin, normal pulses
leg oedema
haemosiderin deposits
lipodermatosclerosis