Derm Drugs

Question 1

Side effects of Glucocorticosteroids

Answer 1

• Immunosuppression
• Steroid rebound
• Skin atrophy (thinning of skin)
• Spread of infection due to immune suppression
• Steroid rosacea
• Stretch marks (striae atrophica)
• Small superficial dilated blood vessels (telangiectasia)
• Purpura rash

Question 2

MoA of topical Corticosteroids

Answer 2

Vasoconstrictive
Anti-inflammatory
Antiproliferative

Question 3

Name a mild topical steroid

Answer 3

Hydrocortisone 1%

Question 4

Name a moderate topical steroid

Answer 4

Modrasone 0.05%
Clobetasone 0.05%
Butyrate 0.05%

Question 5

Name a potent topical steroid

Answer 5

Mometasone 0.1%
Betamethasone 0.1%
Valerate 0.1%

Question 6

Name a very potent topical steroid

Answer 6

Clobetasol 0.05%

Proprionate 0.05%

Question 7

MoA of Calcineurin inhibitors

Answer 7

Immunosuppressors

They suppress lymphocyte activation

Question 8

Side effect of Calcineurin inhibitors

Answer 8

Immunosuppression
Burning sensation on application
Risk of infections
Risk of skin cancer

Question 9

Name some Calcineurin inhibitors

Answer 9

Tacrolimus

Pimecrolimus

Question 10

MoA of Antiseptics

Answer 10

They have bacteriostatic or bacteriocidal effects

Question 11

Name some Antiseptics

Answer 11

Povidone iodine (Betadine) 
Chlorhexidine (Hibitane, Savlon)
Triclosan (Aquasept, Sterzac)
Hydrogen peroxide (Crystacide)
Potassium Permanganate

Question 12

Name an Anti-yeast

Answer 12

Nystatin

Question 13

Name some anti-pruritics

Answer 13

Menthol (Dermacool)
Capsaicin
Camphor
Phenol
Crotamiton (Eurax cream)

Question 14

MoA of Keratinolytics

Answer 14

Softens Keratin

Question 15

Name some Keratinolytics

Answer 15

Salicylic Acid ointment (2-20%)

Benzoyl peroxide

Question 16

Side effects of topical therapies

Answer 16

Burning or irritation
Staining
Contact allergic dermatitis
Local toxicity 
Systemic toxicity