Derm Flashcards
What is the MAJOR function of the skin?
keep body in homeostasis by:
- provide boundaries for body fluid
- protect underlying tissues from microorganisms, harmful subs, and radiation
- modulate body temp
- synthesize vit D
What is the heaviest single organ?
SKIN
percent of body weight is skin?
16%
Layers of the skin
- epidermis (most superficial)
- dermis
- subcutaneous tissue
Appendages of skin
- hair
- nails
- sebaceous and sweat glands
what layer of skin is avasculr?
Epidermis
Layers of epidermis and what are they made of?
- Outer horny stratum corneum–dead keratinized cells
- inner cellular layer
- stratum basale (melanin) and stratum spinosum
Dermis layer: what is found here and what is it made of
- dense collagen and elastic fibers
- sebaceous glands
- sweat glands
- hair follicles
- terminal ends of cutaneous nerves
subcutaneous layer made of?
fatty or adipose tissue
Which skin layer is vascularized?
DERMIS
Melanin
- color?
- determined by?
brownish pigment
-genetically determined and increased by sun exposure
Carotene
- color?
- found where
yellow pigment
-found in SQ fat and heavily keratinized layers
EX: palms and soles
what causes reddening of skin?
oxyhemoglobin–bright red pigment in arteries and caps
De-oxyhemoglobin
- color
- found?
darker blue pigment
-circulates in veins.
Bilirubin
- color
- formed?
yellow-brown pigment
-formed– b/d of heme in RBC
-
What makes skin or BVs look blue vs red?
-scattering of light through turbid superficial layer of skin
Pallor indicates?
anemia
Cyanosis indicates?
- decr oxygen in blood
- decr blood flow in resp to cold
Jaundice results from?
increase bilirubin
Vellus hair
short, fine, less pigmentation
Terminal hair
found where?
coarser, pigmented
on scalp or eyebrow
Causes of generalized itching WITHOUT rash? (8)
- dry skin
- pregnancy
- uremia
- jaundice
- lymphomas
- Leukemias
- drug rxns
- polycythemia vera and thyroid diseases are less common
Sebaceous glands produce?
- found where?
- not found where?
fatty substance secreted onto the skin via hair follicles
-found everywhere on body EXCEPT: palms and soles
Role of nails?
protect distal ends of fingers/toes
fingernails grow approx _____ daily
0.1mm/daily
do toenails grow slower or faster than finger nails?
slower
two types of sweat glands
eccrine glands
apocrine
Eccrine glands
- found?
- open on??
- role?
widely distributed
open directly onto skin surface
control body temp
Apocrine glands
- found?
- stimulated by?
- open into?
- found in axilla and groin
- stimulated by emotional stress
- open into hair follicles
What makes body odor?
bacterial decomposition of apocrine sweat
What happens to appearance of dermis as it becomes less vascular w/ age?
appears paler and more opaque
What happens to skin on back of hands/forearms as we age?
appears thin fragile, loose, transparent
Actinic purpura
- morphology?
- Caused by?
- common in who?
purplish spots caused by blood that has leaked into dermis from poorly supported capillaries
- can develop then fade over time
- common in aging skin
where does hair first recede? then recedes into the….?
first, at the temples and then the vertex
What do you think of if PT presents with hair breaking along the shaft?
tinea capitis
What do you think of it PT presents with hair shedding at the roots?
Telogen effluvium (hair shed from stress) and alopecia areata
MC cancer in us?
SKIN CAs
MC cancers in order and their percents
- basal cell carcinoma–80%
- squamous cell carcinoma–16%
- melanoma–4%
Most prevalent areas for skin CA (3)
- hands
- neck
- head
MC skin cancer?
BCC
Most lethal skin CA?
melanoma
-high met rate
- shiny
- translucent
- grow slowly and rarely met *
- can be pink patch that does not heal
- can be focal scalding
- can appear as a non-healing ulcer
- can appear has a pink plaque with central depression with telangiectasis boarders
BCC
ABCDE-EFG
rule
*which is the most sensitive?
screening for melanoma
A: asymmetry
B: border irregularity
-ragged, notched or blurred
C: Color variations
>2 colors esp blue/black/white (hypopigmentation) or red (inflam rxn to abnormal cells)
D: Diameter
>6mm…size of a pencil eraser
E: Evolution*****MOST SENSITIVE
-changing rapidly in size, s/s, or morphology
E–elevated
F–firm to palpation
G–growing progressively over several weeks
crusted
scaly
ulcerated
-Can met
SCC
RFs for melanoma (11)
- fam hx
- > 50 common moles
- Atypical. or large moles–esp dysplastic
- red or light hair
- solar lentigines
- freckles
- ultraviolet radiation exposure
- light eye or skin color
- severe blistering sunburns in childhood
- immunosuppresion
- person hx of non-melanoma skin cA
- solar lentigines
- rf for what?
acquired brown macules on sun exposed areas
-RF for melanoma
PT counseling for melanoma/skin CA
*which is the best defense against melanoma?
- avoid UV radiation and tanning beds******* best defense against skin CA
- reg use of sunscreen: SPF 30+
Four cardinal techniques?
IPPA
- inspect–look
- palpation–touch/feel
- Percussion-tap
- Auscultation–listen
Characteristics to note when doing skin exam (6)
- color–hyper/hypopigmentation
- moisture
- temp
- texture
- mobility/turgor
- lesions
Color of oxyhemoglobin best done where? Where do you do it for dark-skinned PT?
-fingertips
-lips
-mucous mems
DARK PT: palms and soles
to check skin temp, use?
back of fingertips
If a lesion is present during exam, what do you want to note about it?
- characteristics
- anatomic location and distribution
- patterns
- shapes
- type of lesion–macule, papule, nevus, vesicle
- color
Mist sensitive criteria for the ABCDE rule?
EVOLUTION
Which of the following is not considered a risk factor for the development of melanoma?
A. Light hair and eyes
B. Female gender
C. Severe sunburns in childhood
D. 1-4 dysplastic moles
B
**Males have increased risk of melanoma **
Macule
description?
examples?
flat
cannot palpate
<1cm
EX: freckles, moles