Derm Flashcards
All rashes are assumed to be what unless proven otherwise?
Systemic condition
Systemic complaints to ask with rash:
Sore throat Cold symptoms Joint pain GI sx Fever HA
If patients have a rash and pets what are some possible differentials?
Tinea
Flea bites
Lyme
Even when 100 percent sure rash is not systemic, check the following:
Oral mucosa
Cardiac and respiratory
Abdominal (spleen and liver)
Nails
What rashes favor the inner surfaces of arms and legs?
Atopic dermatitis
Intertrigo
What rashes favor sun exposed areas?
Actinic keratosis
Phototoxic reactions
What rash manifests in the same area as ID reactions like tinea or dyshidrotic eczema?
Acrodermatitis
What rash manifests in the same areas as guttate psoriasis?
Pityriasis rosea
What rashes favor clothing covered areas?
Contact dermatitis
Psoriasis
What rashes manifest in the same areas as Cushing syndrome and acne vulgaris?
Acneiform rashes
This rash manifests as a sub corneal pustule with erosions and honey-colored crusts.
Impetigo
Impetigo is typically caused by what organisms?
Strep or staph
How can impetigo be diagnosed?
Culture and gram stain
Treatment for impetigo?
Beta-Lactamase resistant penicillin or cephalosporin for 5-10 days
Oral agent if patient is sick Topical agent if not sick: Mupirocin TID 5-10 days Altabax Bleach baths
PCN alternatives: erythromycin and clarithromycin
Other superficial skin infections:
Ecthyma
Folliculitis
Perinatal streptococcal dermatitis
This superficial skin infection resembles impetigo but extends through the dermis with underlying punch-out ulcer with exudate and is caused by strep, staph, or pseudomonas.
Ecthyma
This superficial skin infection is hair follicle bases with erythematous papules/pustules that are typically present in axillae and groin and often caused by staph aureus.
Folliculitis
This manifests with redness, warmth, swelling, and tenderness of the proximal nail folds.
Acute paronychia
Acute paronychia is often caused by:
Staph or strep
Acute paronychia tx:
Warm soaks, topical antibiotics, and systemic antibiotics (clindamycin and augmentin)
Chronic paronychia is caused by:
Candida albicans and mixed bacterial flora.
This causes inflammation and edema of the nail bed without pain?
Chronic paronychia
Chronic paronychia tx:
Antifungals and antibiotics
This is a localized skin infection, involving the dermis and subcutaneous tissue with obstruction of local lymphatics.
Cellulitis
Cellulitis is caused by?
GABHS, staph, strep pneumo, or H.flu
This manifests as erythematous, warm, and tender plaques with local swelling and proximal lymphadenopathy.
Cellulitis
Cellulitis tx:
Oral antibiotics- keflex(cephalexin), augmentin for early onset cellulitis
Consider coverage for MRSA
Follow up closely to watch for sepsis
Subclasses of cellulitis?
Necrotizing fasciitis
Erysipelas
This type of cellulitis is caused by group a strep and requires immediate hospitalization?
Necrotizing fasciitis
This type of cellulitis is superficial with sharp, defined borders and is caused by GABHS?
Erysipelas
This is a serious infection of soft tissue and structures around the eye that is caused by GABHS (older children), strep pneumo (younger children), staph aureus, and H. Flu
Orbital and peri orbital cellulitis
Orbital and periorbital cellulitis is more common in what ages?
Children under 5 with the median age of 7
Cardinal symptoms of orbital cellulitis?
Proptosis (bulging of the eye)
Ophthalmoplegia (paralysis or weakness of the eye)
Chemosis (eye irritation)
Caused by increased intraorbital pressure
Other symptoms of orbital cellulitis are:
Limited ocular mobility Pain with eye movement Reduced visual acuity Orbital congestion Headache Fever Lid edema Rhinorrhea Malaise
Periorbital cellulitis is typically caused by:
Trauma to the eyelid of eye
Orbital cellulitis is typically caused by:
Sinus infection
This is caused by circulating staph toxin, which can exfoliate the skin. It usually starts at respiratory site such as nose or mouth?
Staphylococcal scalded skin syndrome
Describe the 2 phases of staphylococcal scalded skin syndrome:
Prodromal phase: bright erythema around mouth, fever, irritability
Exfoliative phase: tender, inflamed peeling skin; red oral mucosa, peeling on trunk
How is staphylococcal scalded skin syndrome diagnosed?
Nikolskys sign: rubbing erythematous skin sideways causes superficial epidermis to separate from deeper skin layers and slough off.
What is staphylococcal scalded skin syndrome called in neonates?
Ritter’s disease
Staphylococcal scalded skin syndrome can be related to what if peeling is not present?
Nonstreptococcal scarlet fever
Treatment of staphylococcal scalded skin syndrome?
ICU, systemic anti-staph antibiotic
This is caused by GABHS and manifests as red, roughened, diffuse, sandpaper-like rash.
Scarlett fever
Symptoms of scarlet fever:
Blanching rash in groin, axillae, abdomen, and trunk
Appears after 24 hours
Can have pastia’s lines (linear petechia in flexural creases)
White or strawberry tongue
Circumoral pallor
Desquamation in 1-3 weeks
Diagnosis of scarlet fever requires?
Rapid strep test or throat culture
This begins as red macules or papules and within a week, expands to a large, annular, and erythematous rash 5-15 cm in diabetes with a pale center?
Lyme disease
Lyme disease is caused by?
Borrelia burgdorferi spirochete
The early stage of Lyme disease has symptoms of?
Fever, fatigue, malaise, headache, neck/joint stiffness, Lyme meningitis
The early disseminated disease of Lyme disease symptoms include:
Multiple erythema migrans (3-5 weeks after bite), facial palsy, aseptic meningitis, cardiac involvement (AV block and myocarditis), MSK pain
Long term (months or years) effects of Lyme disease?
Chronic arthritis and neuro sequelae
Diagnosis of Lyme disease?
Serology for Borrelia burgdorferi
Treatment of Lyme disease?
14-21 days of antibiotics
- kids over 8- doxycycline 100mg BID
- kids under 8- amoxicillin 25-50mg/kg TID or ceftriaxone daily for persistent disease sx
Treatment of neurologic Lyme disease?
Ceftriaxone 2g daily IV 14 days
Doxy 200-400mg PO BID 10-28 days
Prophylaxis of Lyme disease?
Single dose of doxy 200mg
This is caused by neisseria meningitidis which causes leakage and vascular injury which may lead to DIC, irreversible shock, and multi system organ failure?
Meningococcemia
Symptoms of meningococcemia include:
Upper respiratory prodrome followed by high fever, chills, HA, toxicity, and hypotension
Fulminant purpural, urticarial, maculopapular, and petechial eruptions over trunk and extremities
Treatment for meningococcemia?
High dose PCN G q4-6 hours
Alternatives- cefotaxime, ceftriaxone, chloramphenicol
Prophylaxis of meningococcemia?
Vaccination at age 11 before starting college
Ages 2-5 for high-risk children
This rash is a breakdown of the skins natural barrier due to chemical irritation (urine, proteolytic enzymes, and moisture in urine/feces)?
Irritant contact diaper rash (dermatitis)
This rash is a type of diaper dermatitis that has irritant, dry, red patches with laceration of the skin folds?
Chemical rash
This type of diaper rash has hyperpigmentation and erythema at folds and diaper edges?
Mechanical rash from diapers
When do you use anticandidal agents in any clinically significant diaper dermatitis?
If present for greater than 72 hours, regardless of morphology as C. albicans is likely playing a secondary role
This is a mild illness caused by a single- stranded positive-sense RNA virus with a glucolipid envelope that is acquired from respiratory secretions and invades respiratory epithelium.
Rubella or German measles
Symptoms of rubella?
Lymphadenopathy, erythematous macular papular discrete rash, mild pharyngitis, conjunctivitis, anorexia, HA, malaise, low grade fever
How is rubella diagnosed?
Viral isolates from NP secretions
How is rubella prevented?
MMR vaccine at 12-15 months and 4-7 years
May give IG for pregnant, nonimmunized, exposed women and then vaccinate postpartum
This causes an ill, miserable child with an upper respiratory catarrhal prodromal phase consisting of Kopliks spots on buccal mucosa, conjunctivitis, rhinitis, OM, and a dusky, red maculopapular rash on face that spreads to trunk.
Measles
Is measles or rubella teratogenic to pregnant women?
Rubella
Measles treatment?
Supportive care
Avoid ASA
This occurs between 6 months to 3 years and has an abrupt onset of illness with high fever. Child may have URI sx, OM, diffuse erythema of posterior pharynx and soft palate, GI sx, and a macular erythematous rash during febrile phase or after fever resolves.
Roseola
Roseola management?
Symptomatic care
This is caused by parvovirus B19 with symptoms of low-grade fever, HA, child’s, followed by erythematous facial rash, and lacy, maculopapular rash.
Fifth’s disease ( erythema infectiousum)
Who is most affected by fifths disease?
School-ages kids in late winter and spring
What could fifths disease cause in pregnant women?
Hydrops fetalis in fetus
This is caused by coxsackievirus A16 and enterovirus 70 and presents with vesicles or red papules found on tongue, hands, and feet (rash often appears when fever abates)
Hand foot and mouth
Hand foot and mouth treatment?
Symptomatic
Tylenol, Benadryl, and Maalox/kaopectate for oral lesions.
Avoid salicylates!
This is caused by the herpesvirus varicellae and causes a prodrome of low-grade fever, URI symptoms, a maculopapular varicella crop lesions, diffuse vesicles and erythema, poor appetite, malaise, and pruritus.
Varicella