derm Flashcards
epidermis two layers
outer: horny
- horny stratum corneum of dead keratinized cells
inner: cellular
- stratum basale
- stratum spinosum (malpighian): melanin and keratin are formed here
Blanchable vs nonblanching lesions
Blanchable:
- erythematous
- suggest inflammation
Nonblanching lesions:
- petechiae
- purpura,
- vascular structures (cherry angiomas, vascular malformations)
- not erythematous, but rather BRIGHT red, purple
- blood has extravasated out from the capillaries into the surrounding tissues.
dermis
layer of interconnecting collagen and elastic fibers
containing appendages:
- pilosebaceous glands (oil glands)
- sweat glands
- hair follicles
- terminals of the cutaneous nerves
Pallor, cyanosis and jaundice
Pallor: anemia
Cyanosis:
- decreased oxygen in blood
- decreased blood flow from cold environment
Jaundice:
- increased bilirubin
Hair two types:
vellus:
- Short
- fine
- inconspicuous
- relatively unpigmented
Terminal:
- Coarser
- thicker
- more conspicuous
- usually pigmented
-ex: scalp hair and eyebrows
What do pilosebaceous glands (oil glands) produce? and where are they not found
produce:
- Fatty substance secreted onto skin surface through hair follicles
not found?
- Palms and soles
apocrine sweat glands vs eccrine sweat glands
Apocrine:
- Axillary and genital regions
- open into hair follicles
- bacterial decomposition of apocrine sweat = body odor
Eccrine:
- widely distributed
- open directly onto skin surface
- control body temperature by sweat production
What causes body odor?
Bacterial decomposition
Angle between the proximal nail fold and nail plate is normally less than____ degrees.
180 degrees
Fingernails grow approximately ___ mm daily; toenails grow more_____ (fast vs slow).
0.1 mm
toenails grow more slow
What causes generalized itching w/o apparent rash?
Dry skin
Uremia
Jaundice
Lymphomas
Leukemia
Drug reactions
Polycythemia vera
Thyroid disease
What is hair shedding at the roots common in?
Telogen effluvium: + hair pull test
Alopecia areata
When does hair break along the shaft?
Damage from hair care
tinea capitis
Scarring vs nonscarring hair shedding
non-scarring hair shedding in young women?
- Iron deficiency anemia
- Hyper or hypothyroidism
scarring:
- central centrifugal scarring alopecia
- discoid lupus erythematosus
What are the ABCDEs of melanoma?
Asymmetry
Border irregularity
Color variation
Diameter >6mm
Evolution***
Cutaneous wound repair process: 4 phases
1) coagulation
2) inflammatory phase
3) proliferative migratory phase (tissue formation)
4) remodeling phase
what are the dimensions of this papule
▪ Measure in the
longest axis first, then
in the perpendicular
axis
* e.g., this papule is
6x4 mm
magnification tools + dermatoscopes
▪ Inexpensive magnifying
glasses may help detect
fine details
* Avoid LED lights, which
cast a blue hue
▪ Dermatoscopes help
evaluate patterns in
pigmented lesions
* Requires additional
training to become
proficient
Blanching vs. Non-blanching
Diascopy!!
morphology
used by dermatologists to describe the form and structure of skin lesions
two steps in establishing the morphology of any given skin condition:
1. Careful visual and tactile inspection
2. Application of correct descriptors
what are the main primary lesions
Macule, patch: Flat, color change only
Papule, plaque: raised, palpable
Vesicle, bulla: serous fluid-filled space in epidermis
Wheal: an edematous papule or plaque
Nodule, Tumor: raised lesion deeper in skin
Pustule, furuncle, abscess: pus-filled space
Cyst: a sac-like nodule that has an epithelial lining containing fluid
or debris
special lesions: not primary or secondary; what are they
TELANGIECTASIA
- fine, irregular red lines
COMEDONES
- plugs of whitish or blackish sebaceous
- material lodged in the pilosebaceous follicles
MILIA
- whitish nodules with no visible opening to the skin surface
- 1-2 mm in diameter
BURROWS
- tortuous, long tunnel in the
epidermis
ex: scabies
Distribution vs Configuration
Distribution:
- location(s) on the body
Configuration:
- how the lesions are
arranged or relate to each other
- lesions are grouped but also follow a linear pattern around the trunk
- This is an example of a segmentalor dermatomal distribution
Clubbed fingernails description
- Soft nail beds. The nails may seem to “float
- The nails form a sharper angle with the cuticle.
- The nail curves downward so it looks like the round
part of an upside-down spoon.