Depressive DIsorders Flashcards

1
Q

Depressive Disorderes

DM 5 list (shortened)

A
  • Major Depressive Disorder (MDD)
  • Persistent Depressive DIsorder
  • Pre-Menstrual Dysmorphic Disorder
  • Disruptive Mood Dysregulation Disorder
  • Substance/Med-induced
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2
Q

Depression vs Sadness

A

Depression = less/unresponsive to positive environmental stimuli

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3
Q

MDD

Dx

A

5+ s/s for MINIMUM 2 WEEKS (change from previous functioning)

  • Depressed mood
  • Loss of interest to activities
  • Weight change
  • Insomnia/hypersomnia
  • Psychomotor agitation/retardation
  • Energy loss
  • Less concentration
  • Guilt/worthlessness
  • Death/suicide thoughts

Depression Is Worth Studiously Memorizing Extremely Grueling Criteria, Sorry.

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4
Q

MDD

DSM specifiers

  • anxiety
  • mixed features
  • melancholic features
A
  • anxiety
  • min 2 s/s
  • mixed features = manic-like, but not timeline for bipolar, can develop to bipolar
  • melancholic features = pleasure loss, worse in morning
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5
Q

2ndary depression

  • drug
  • metabolic
  • Neuro
  • Pancreatic cancer
A
  • drug = opioid
  • metabolic = hypothyroidism
  • Neuro = Parkinson’s, tumor, stroke
  • Pancreatic cancer = interleukins
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6
Q

MDD

MC comorbidities

A

Anxiety disorder
Substance Use
Personality Disorder

Also: med condition, environ stress, dysthmia (double depression)

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7
Q

MDD

Endocrine bases

A

Cortisol not shutting down when chronically flooding brain

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8
Q

MDD

Striatum

A

sluggish movement

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9
Q

MDD

Neocortex

A

Concentration

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10
Q

MDD

Amygdaloid Body

A

Anxiety

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11
Q

MDD

Hypothalamus

A

Sleep Appetite

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12
Q

MDD

Hippocampus

A

Memory problems

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13
Q

Best chance of full remission w/ patients who

A

pursue Tx

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14
Q

ADDs good for actute/longterm Tx?

A

long-term

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15
Q

Suicide

Investigate:

A
  • Plan?
  • Plan lethality?
  • Access to means?
  • Intent?
  • Oppose/Accept plan?
  • Social Support?
  • 24/7 Observation?
  • Comorbidity?
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16
Q

MDD

Who?

A

Female
White
Old
Widow

17
Q

MDD

Treatment

A

Mild/Moderate = ADDs

Severe = ADD + Psychotherapy

Refractory = Transcranial Magnetic Stimulation (TMS), Electroconvulsive Therapy (ECT)

18
Q

ADD treats ____ s/s

A

Psych (1st ) + Somatic s/s

19
Q

MDD

Thought distortion

A

Give too much value to unrealistic thought

20
Q

Depressed mood + 2 other depressive s/s FOR 2 YEARS+

  • +/- periods of major depression (double depression)
  • NO if d/t substance/med
A

Persistent Depressive Disorder (Dysthymia)

Dx

21
Q

Severe temper outbursts w/ underlying persistent angry mood

  • 3+ outbursts/week
  • Irritable mood + outbursts AT LEAST 1 YEAR
  • Before 10 y/o (NO dx after 18 y/o)
  • NO w/ ODD
A

Disruptive Mood Dysregulation Disorder (DMDD)

Dx

22
Q

DMDD

Who?

A

males

23
Q

DMDD

Tx

A

Cognitive behavioral Therapy (children)

24
Q

MDD

Exclude for Bereavement/Grief?

A

NO

depression s/s LESS than 2 months after death of loved one

25
Q
5 s/s + at least one (*)
MIN 2 cycles
***Affective Lability***
***Irritability***
***Depressed mood***
***Anxiety/ Tension***
*decreased interest
*Poor concentration
*Fatigue
*appetite change
*hypersomnia/insomnia
*overwhelmed
*breast/joint tenderness, weight gain
A

Premenstrual Dysphoric Disorder

26
Q

Mania = s/s MIN 1 WEEK
Hypomania = s/s MIN 4 days
NO d/t RX

3+ s/s:

  • grandiosity
  • Less sleep need
  • Pressured speech
  • DIstractability
  • UP activity, agitation
  • Consequential Behavior
  • NO d/t Rx
A

Mania/Hypomania

Dx

27
Q

MUST HAVE:

  • lost of pleasure
  • inability to respond to pleasurable stimuli

+3

  • Depressed mood
  • worse in morning (diurnal variation)
  • Terminal insomnia
  • psychomotor agitation
  • weight loss
  • guilt
A

DM specifiers

Melancholia

28
Q

Bereavement vs. Depression

A

Now classified as Major depression if meet timeline

DO NOT need extreme severity or suicide.

Seen as trigger to episode

ADD meds work

29
Q

Catecholamine hypothesis

A

NE lack is cause of Depression