Depression Case Flashcards

1
Q

t/f: antidepressants are habit forming

A

f!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

SSRI’s affect what NT in the brain

A

serotonin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

SNRI’s affect what 2 hormones/NT in the brain

A

serotonin
NE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

2 first line meds for dpn

A

SSRI
SNRI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

name 5 SSRIs

A

citalopram (celexa)
escitalopram (lexapro)
fluoxetine (prozac)
paroxetine (paxil)
sertraline (zoloft)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

name 3 SNRI’s

A

desvenlafaxine (pristiq)
duloxetine (cymbalta)
venlafaxine (effexor)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

TCA’s are useful for what type of depression

A

melancholic (profoundly sad)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

which 2 antidepressants carries a risk of lethal overdose

A

TCA
MAOI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

name 1 TCA

A

amitriptyline (Elavil)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

name 1 tetracyclic antidepressant

A

buproprion (wellbutrin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

name 2 MAOI’s

A

isocarbozid (marplan)
penelzine (nardil)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what 2 antidepressants can be helpful for concurrent insomnia/anxiety

A

mirtazapine (remeron)
penelzine (desyrel)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what 2 antidepressants can be helpful for resistant depression

A

aripiprazole (abilify)
quetiapine (seroquel)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

6 clinical uses of antidepressants

A

depression
anxiety
chronic pain
premenstrual dysphoric disorder (PMDD)
smoking cessation
eating disorders

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

which antidepressants are associated with deadly withdrawal

A

tick question - none!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

adverse effects of SSRI’s (6)

A

serotonic activity ->
nausea
GI upset
diarrhea
diminished sexual fxn
HA
weight gain

17
Q

2 symptoms of SSRI discontinuation syndrome

A

dizzy
paresthesias

18
Q

s.e of SNRIs

A

serotenergic effects

PLUS

noradrenergic effects:
increased BP and HR
insomnia, anxiety, agitation

19
Q

s.e of TCAs (5)

A

anticholinergic ->
dry mouth
constipation
urinary retention
blurred vision
confusion

20
Q

sx of TCA discontinuation syndrome

A

cholinergic rebound
flu like sx

21
Q

what antidepressant has the highest rates of sexual effects

22
Q

besides sexual effects, 2 other s.e of MAOI’s

A

orthostatic hypotn
weight gain

23
Q

very last line antidepressant that should only be used as a refractory option

24
Q

mc method of suicide attempts

A

drug overdose
esp TCAs

25
how to manage GI s.e of antidepressants
take after meals
26
how do you manage sedation s.e of antidepressants
take at HS
27
least sedating antidepressant
SSRIs
28
least sedating SSRI
prozac
29
3 sedating antidepressants
remeron celexa effexor
30
how to manage agitation s.e of antidepressants
switch to more sedating antidepressant
31
2 antidepressants with least sexual side effects
wellbutrin remeron (also consider PDE-5)
32
antidepressants that are good for anxiety/panic
paxil remeron effexor TCAs avoid benzos
33
2 methods to manage orthostatic hypotn s.e of antidepressants
hydration education on movement
34
you should taper antidepressants over __ weeks
4 slower if symptomatic
35
2 OTC options for depression
st. john's wort SAMe
36
t/f: st john's wort can be taken with a serotenergic agent
f!