Depression Flashcards
Duration of depressive episodes in referred samples
5-8 months
Duration of depressive episodes in community samples
3-6 months
Fluoxetine: what is the number needed to treat (NNT)
5
SSRIs: what is the number needed to treat (NNT)
9
TADS: which antidepressant it tests
Fluoxetine
TADS: when it took place
2006
Researcher on genetics of schizophrenia and depression, life events, replicated the serotonin transporter polymorphism findings (name)
Kenneth Kendler
Depression: heritability
40-65%
Kendler et al, 1997: genetic liability to MD increases the risk of exposure to …
stressful life events (SLEs)
… et al, 1997: genetic liability to MD increases the risk of exposure to stressful life events (SLEs).
Kendler
Kendler et al, … (Year): genetic liability to MD increases the risk of exposure to stressful life events (SLEs).
1997
The … gene mediates the influence of environmental adversity on depression (Caspi, Moffitt et al 2003)
serotonin transporter (SERT)
Maria … developed Children’s Depression Inventory (CDI) as an adjustment of the Beck Depression Inventory (BDI) in 1979
Kovacs
Maria Kovacs developed … as an adjustment of the Beck Depression Inventory (BDI) in 1979
Children’s Depression Inventory (CDI)
… ; Woodward, 2002: New Zealand depression cohort
Fergusson
Peter Lewinsohn directs the … Adolescent Depression Project, started in 1985
Oregon
Peter … directs the Oregon Adolescent Depression Project, started in 1985
Lewinsohn
… is the father of behavioral treatments of depression (Behavioral activation)
Lewinsohn
Lewinsohn is the father of … treatments of depression
behavioral
Melancholic features: …, lack of reactivity to usually pleasurable stimuli, distinct quality of depressed mood, worse in the morning, early-morning awakening, psychomotor agitation or retardation, anorexia or weight loss, excessive or inappropriate guilt.
loss of pleasure in all activities
Melancholic features: loss of pleasure in all activities, …, distinct quality of depressed mood, worse in the morning, early-morning awakening, psychomotor agitation or retardation, anorexia or weight loss, excessive or inappropriate guilt.
lack of reactivity to usually pleasurable stimuli
Melancholic features: loss of pleasure in all activities, lack of reactivity to usually pleasurable stimuli, …, worse in the morning, early-morning awakening, psychomotor agitation or retardation, anorexia or weight loss, excessive or inappropriate guilt.
distinct quality of depressed mood
Melancholic features: loss of pleasure in all activities, lack of reactivity to usually pleasurable stimuli, distinct quality of depressed mood, …, early-morning awakening, psychomotor agitation or retardation, anorexia or weight loss, excessive or inappropriate guilt.
worse in the morning
Melancholic features: loss of pleasure in all activities, lack of reactivity to usually pleasurable stimuli, distinct quality of depressed mood, worse in the morning, early-morning awakening, …, anorexia or weight loss, excessive or inappropriate guilt.
psychomotor agitation or retardation
Melancholic features: loss of pleasure in all activities, lack of reactivity to usually pleasurable stimuli, distinct quality of depressed mood, worse in the morning, early-morning awakening, psychomotor agitation or retardation, anorexia or weight loss, ….
excessive or inappropriate guilt
TADS: Treatment for Adolescents With … Study
Depression
…(name): researcher on antisocial personality (Adolescence-Limited vs Life-Course Persistent Antisocial Behavior), gene x environment interactions (MAOA polymorphism, SERT short and long allele)
Terrie Moffitt
… (name), researcher in depression and suicide in adolescents and the familial transmission of suicide, director of the Services for Teens at Risk (STAR).
David Brent
