Depression Flashcards
Unipolar Depression
Individual has no history of mania
Behaviour returns to normal when the depression lifts
Bipolar Disorder
Experiences periods of mania that alternate with periods of depression.
How common is Unipolar Depression?
15% worldwide population will experience a severe episode.
Twice as many women (but milder).
Dramatic increases in younger ages.
White Americans have higher rates than African-Americans.
85% recover without treatment but 40% will have a further episode.
Unipolar Depression Symptoms
Feeling miserable, empty, humiliated Poor memory Headaches, indigestion, dizziness Appetite and Sleep Disturbances 7-15% commit suicide Perform as well as non-depressed people but think they have done a lot worse.
The 5 Functioning Areas Affected by Depression
Emotional - Feeling miserable, empty, humiliated
Motivational - Lacking Drive and Spontaneity
Behavioural - Less active, less productive
Cognitive - Pessimistic, blames themselves
Physical - Headaches, general pain
Diagnosing Unipolar Depression
A major depressive episode is a period of two or more weeks marked by 5 or more symptoms of depression.
In extreme cases, symptoms are psychotic such as hallucinations.
DSM-5 list several types of depression…
Major Depressive Disorder - People who experience a major depressive episode with no history of mania.
Dysthymic Disorder - People who experience a longer lasting (2 years +) but less disabling pattern of depression.
Premenstrual Dysphoric Disorder - Women who repeatedly experience depressive symptoms during the week before menstruation.
Disruptive Mood Regulation Disorder - A combination of persistent depressive symptoms and recurrent outbursts of severe temper.
Stress and Unipolar Depression
People with depression experience a greater number of stressful life events during the month before their onset of symptoms.
Biological Model of Unipolar Depression
Genetic Factors - twin studies, family lineage
Biochemical Factors - neurotransmitters, hormone release
Biological Treatments of Unipolar Depression
Antidepressant Drugs:
MAO Inhibitors:
Works by slowing down the body’s production of MAO. MAO breaks down norepinephrine and inhibitors stop this breakdown occurring. This leads to a rise in norepinephrine activity and a reduction in depressive symptoms. 50% of patients are helped by these.
Biological Treatments of Unipolar Depression
Antidepressant Drugs:
Tricyclics:
To prevent neurotransmitters from remaining in the synapse for too long, a pump-like mechanism recaptures the NT and draws it back into the presynaptic neuron. This reuptake process draws in too much NT for some people and this reduction is thought to cause depression. Tricyclics block the reuptake process, thus increasing NT activity in the synapse.
Biological Treatments of Unipolar Depression
Antidepressant Drugs:
Second Generation Antidepressants:
Structurally different from tricyclics and MAO inhibitors.
These drugs increase the activity of serotonin specifically and no other NT.
Named SSRI’s.
Biological Treatments of Unipolar Depression
Brain Stimulation:
Vagus Nerve Stimulation
Transcranial Nerve Stimulation
Deep Brain Stimulation
Psychological Models of Unipolar Depression
Psychodynamic Model - no research
Behavioural Model - modest research
Cognitive Model - considerable research
Psychodynamic Model
Link between grief and depression.
When a loved one dies, an unconscious process begins and the mourner regresses back to the oral stage. They merge their identity with that of the lost person, symbolically regaining them. This reaction is temporary but if grief is severe, then depression results.