Dengue Fever Flashcards
Vector
Aedis aegypti - most common
Aedis albopictus
Malnutrition protective or not protective
Protective
More dangerous sequence of infection
Serotype 1 followed by serotype 2
Warning signs
- Abdominal pain/tenderness
- Persistent vomiting
- Mucosal bleeding
- Clinical signs of fluid accumulation
- Lethargy/restlessness
- Liver enlargement
- Increase in Hct or decreasing platelet count
Earliest abnormality in CBC
Progressive decrease in WBC
Phases of dengue fever
- Febrile phase
- Critical phase
- Recovery phase
Confirmatory diagnosis of dengue fever
Viral culture isolation or PCR
Treatment for dengue with warning signs
Hydrate 5-7mkh x1-2hrs then 3-5mkh x2-4hrs then 2-3mkh
If worsened: 5-10mkh x1-2hrs
Treatment for severe dengue in compensated shock
Hydrate 5-10mkh x1hr
If improved, proceed to hydration as done in dengue with warning signs
If worsened, hydrate 10-20mkh x1hr then 7-10mkh x1-2hrs then same as dengue with warning signs
If Hct decreases to <40% in women, <45% in men, transfuse
Treatment for severe dengue in hypotensive shock
Hydrate crystalloid or colloid 20mkh x15mins
If improved, 10mkh x1hr then proceed as with dengue with warning signs
If worsened, colloid 10-20mkh x30mins-1hr then 7-10mkh x1-2hrs then crystalloid as with dengue with warning signs
If Hct decreases to <40% in women, <45% in men, transfuse
Rising or persistently high Hct + unstable VS
Indicates active plasma leakage, must hydrate
Rising or persistently high Hct + stable VS
No extra IVF
Decreased Hct + unstable VS
Indicates major hemorrhage, must transfuse
Decreased Hct + stable VS
Indicates hemodilution, must stop IVF
Repeated large volumes of 0.9% saline will lead to what
Hyperchloremic acidosis
