Dengue Flashcards

1
Q

Cellular targets of Dengue?

A

Monocytes
Splenic macrophages

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2
Q

Receptor used?

A

Heparan sulfate

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3
Q

Vectors used?

A

Aedes egypti
Aedes albopictus

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4
Q

How many serotypes?

A

4
DEN1-4

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5
Q

Define primary and secondary infection.

A

Primary-initial infection

Secondary-second infection of different serotype

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6
Q

3 stages of clinical manifestations?

A
  1. Dengue fever
  2. Dengue hemorrhagic fever
  3. Dengue Shock Syndrome
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7
Q

2 xtics of Dengue fever

A

High fever
Arthralgia and Myalgia

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8
Q

2 xtics of DHF

A

Thrombocytopenia
Raised Hematocrit

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9
Q

2 xtics of Dengue Shock Syndrome

A

Hypotension
Clammy skin

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10
Q

Vaccines?

A

Dengvaxia
(subcutaneous)

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11
Q

Treatment?

A

Replacement of plasma expander and elctrolytes

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