Dengue Flashcards
1
Q
Cellular targets of Dengue?
A
Monocytes
Splenic macrophages
2
Q
Receptor used?
A
Heparan sulfate
3
Q
Vectors used?
A
Aedes egypti
Aedes albopictus
4
Q
How many serotypes?
A
4
DEN1-4
5
Q
Define primary and secondary infection.
A
Primary-initial infection
Secondary-second infection of different serotype
6
Q
3 stages of clinical manifestations?
A
- Dengue fever
- Dengue hemorrhagic fever
- Dengue Shock Syndrome
7
Q
2 xtics of Dengue fever
A
High fever
Arthralgia and Myalgia
8
Q
2 xtics of DHF
A
Thrombocytopenia
Raised Hematocrit
9
Q
2 xtics of Dengue Shock Syndrome
A
Hypotension
Clammy skin
10
Q
Vaccines?
A
Dengvaxia
(subcutaneous)
11
Q
Treatment?
A
Replacement of plasma expander and elctrolytes