Chukungunya Flashcards
1
Q
Baltimore Class?
A
IV
2
Q
Structure?
A
Enveloped and icosahedral
3
Q
Vector?
A
Aedes aegypti
4
Q
Cellular targets
A
Epithelial
Endothelial
Firbroblasts
5
Q
Pathogenesis
A
- Infects skin fibroblasts and dermal macrophages–>reaches lymph nodes
- Reaches spleen and liver in acute phase
- Reaches muscles and joints through blood.
6
Q
Clinical manifestations…list the two phases.
A
Acute phase
Chronic phase
7
Q
Acute phase symptoms?
A
Chik sign
Severe arthralgia and myalgia
8
Q
Chronic stage manifestation?
A
Recovery but joint pain persists
9
Q
High risk groups (2 marks)
A
Elderly
Newborns
