Dementia syndromes Flashcards

1
Q

Reversible causes of dementia

A
  • intracranial and systemic causes
  • normal pressure hydrocephalus
  • subdural haematoma
  • cerebral tumours
  • tertiary syphilis
  • alcohol
  • anoxia
  • hypoglycaemia
  • myxoedema
  • vitamin deficiencies
  • drug or chemical poisoning
  • pseudodementia
  • renal and hepatic disease
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2
Q

Alcohol related dementia

A
  • accounts for 12% of young onset dementia
  • prolonged heavy use can cause damage to limbic structures and frontal lobes
  • memory impairment can improve following a prolonged abstinence
  • autobiographical memory is affected
  • confabulation can occur
  • neuroimaging may be non-specific or may show generalised cortical atrophy with frontal preponderance
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3
Q

Normal pressure hydrocephalus

A
  • dliation of the cerebral ventricles (especially 3rd)
  • normal CSF pressure on LP
  • -dementia, gait ataxia and incontinence
  • 0.4% of elderly
  • dementia is subcortical and potentially reversible
  • 50% are idiopathic
  • 50% are secondary to mechanical obstruction of CSF flow across the meninges due to infection, trauma, SAH
  • urinary incontinence is a late symptom
  • CT shows enlarged lateral ventricles
  • needs a ventriculo-peritoneal shunt
  • gait improves with shunting
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4
Q

Chronic subdural haematoma

A
  • subdural veins are more vulnerable to tears in older people due to cortical shrinking
  • -30% have bilateral SDH
  • history of head injury occurs in only 50% patients
  • may not be recent trauma
  • headache, drowsiness, altered consciousness, confusion
  • CT scan shows crescent shaped haematoma compressing sulci and midline shift (may not be seen in first 3 weeks)
  • surgical burr holes or steroids
  • mortality is 10%
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