Dementia Day Lectures

Question 1

Prevalence of AD is fastest growing in what age group?

Answer 1

> 80

Question 2

annual tx costs for AD in the US is

Answer 2

~200 billion

Question 3

70 yo M pt in with daughter who confirms memory complaint, which is objetivley impaired for her age. However pt reports normal acitivties of daily living and no changes in general cognition otw. Pt denies being demented. Dx?

Answer 3

mild cognitive impariment (MCI)

Question 4

memory loss ≠dementia, can progresses faster in AD vs gen pop; possibly the earliest phase in AD; clinically diagnosed

Answer 4

Amnestic MCI

Question 5

deficits in 1+: memory complex attn, exec function, learning/memory, language, percepetual/motor, social cogn
sfg imparments
diagnosis in clear sensorium

Answer 5

Dementia

hint: Mild (can fx alone) vs Major (can’t live independently)

Question 6

• occurs 30-60,with family hx with ∆preseniline1/2 or ∆APP

Answer 6

Early Onset AD

hint: mut on chrom 1, 14, 21 (APPgene)

Question 7

mot common form of dz; devs after age 60 with a combo of contributory factors. Apoprot E4 implicated

Answer 7

Late Onset AD

hint: chrom 19

Question 8

atrophy atrophy (frontal + parietal + hippo) w/ hydrocephalus exvacuo

Answer 8

AD

hint: most common cause of dementia