Dementia

Question 1

What is Dementia?

Answer 1

Progressive neurodegenerative disorder that affects all aspects of higher cognitive function including memory, intellect, personality and behaviour

Question 2

What area of the brain does dementia mostly affect?

Answer 2

Primarily affects cells of cerebral cortex

Question 3

What mechanism of neuro-degeneration affects dementia?

Answer 3

Accumulation of misfolded proteins proteins within the cells of the cerebral cortex causing the formation of toxic fragments called beta amyloids

These damage synapses etc disrupt cellular function and leading to inflammation of nerual tissues

Question 4

What is the most common form of dementia?

Answer 4

Alzheimers

Question 5

How many people have dementia?

Answer 5

35.7 million people

Question 6

Name the different types of dementia

Answer 6

Vascular
Lewy-Body
Fontrotemporal Dementia
Alzhiemers

Question 7

What is vascular Dementia?

Answer 7

Second most common

Characterised by multiple mini strokes throughout the cerebral cortex

Question 8

What is Lewy Body Dementia?

Answer 8

Accumulation of misfolded proteins, particularly Lew Body protein

Shares features with Alzheimers and Parkinson’s

Question 9

What is Frontotemporal Dementia?

Answer 9

Progressive degeneration of frontol and or temproal lobes of the brain

Therefore, symptoms include behaviour, language, personality rather than memory