Dementia

Question 1

features of Lewy body dementia

Answer 1

> 65
gradual decline

Question 2

pathophysiology of Lewy body dementia

Answer 2

deposits of protein a-synuclein in neurones, interferes with signals

Question 3

specific symptoms to lewy body dementia

Answer 3

difficulty learning new things
disturbed sleep
hallucinations

Question 4

treatment of dementia

Answer 4

speech and language therapy
cognitive stimulation
memory cafes
physio
meds to reduce symptoms

Question 5

symptoms of dementia

Answer 5

confusion
memory loss

Question 6

features of Alzheimers

Answer 6

> 65
gradual decline, affects short term memory first as hippocampus affected

Question 7

pathophysiology of Alzheimers

Answer 7

beta amyloid plaques get between neurones, impair brain function

and 3R + 4R tau proteins tangle inside neurones

=apoptosis of neurones

Question 8

what causes the cognitive symtypoms of Alzheimers?

Answer 8

decreased ACh in nucleus basalis

Question 9

risk factors for alzheiers

Answer 9

familial- early onset
down’s syndrome
APOE-e4

Question 10

features of vascular dementia

Answer 10

> 65
decline after each stroke to lose more functions
multi infarct dementia

Question 11

pathophysiology of vascular dementia

Answer 11

progressive loss of brain function from atherosclerosis
=chronic ishcaemia
=ischaemic stroke
=liquefactive necrosis
=loss of brain function

Question 12

features of frontotemporal dementia

Answer 12

40-60
memory spared at first, but behavioural symptoms

Question 13

pathophysiology of frontotemporal dementia

Answer 13

pick bodies (tangles of 3R tau protein) = apoptosis

atrophy of frontal then temporal lobes