Delirium Flashcards

1
Q

What are the clinical features of delirium?

A
  • Acute behavioural changes
  • Altered cognitive function
  • Inattention
  • Disorganised thinking
  • Altered perception
  • Altered physical function
  • Altered social behaviour
  • Altered level of consciousness
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2
Q

What are the potential warning signs for delirium?

A
  • Falling

- Loss of appetite

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3
Q

How do symptoms of delirium change throughout the day?

A
  • Lucid intervals during the day

- Worsening of symptoms at night

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4
Q

What are the types of delirium?

A
  • Hyperactive
  • Hypoactive
  • Mixed
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5
Q

Which type of delirium is most common?

A

Hypoactive

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6
Q

Describe hyperactive delirium.

A
  • Increased sensitivity to immediate surroundings
  • Agitation, restlessness, sleep disturbance, and hypervigilance
  • Wandering is also common
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7
Q

Describe hypoactive delirium.

A
  • Patient may be lethargic
  • Reduced mobility and movement
  • Lack of interest in daily activities
  • Reduced appetite
  • Quiet and withdrawn
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8
Q

What are the predisposing factors to delirium?

A
  • Older age (over 65 years)
  • Cognitive impairment (such as dementia)
  • Frailty/multiple comorbidities (such as stroke or heart failure)
  • Significant injuries such as hip fracture
  • Functional impairment (for example immobility or the use of physical restraints such as cot sides)
  • Iatrogenic events (such as bladder catheterization, polypharmacy, or surgery)
  • History of, or current, alcohol excess
  • Sensory impairment (such as visual impairment or hearing loss)
  • Poor nutrition
  • Lack of stimulation
  • Terminal phase of illness
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9
Q

What are the precipitating factors to delirium?

A
  • Infection
  • Metabolic disturbance (blood glucose, electrolytes)
  • Medication (benzos, opiates, anti-Parkinson meds, TCAs, lithium, antipsychotics etc)
  • Uncontrolled pain
  • GI (constipation, faecal impaction, malnutrition)
  • Alcohol intoxication or withdrawal
  • Urinary retention
  • Cardio/resp/endo/neuro disorders
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10
Q

What investigation might be done when investigating the cause of delirium?

A
  • Vitals (inc blood glucose)
  • Urinalysis
  • Sputum culture
  • FBC
  • Folate and B12 deficiency
  • U&Es
  • HbA1c
  • Calcium
  • LFTs
  • ESR, CRP
  • Drug levels
  • TFTs
  • CXR
  • ECG
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11
Q

What are the supportive management strategies for delirium?

A
  • Consistent nursing and medical team, gentle re-orientation, calm and consistent care
  • Access to aids such as glasses, hearing aids, walking aids
  • Enable the patient to do what they can for themselves
  • Access to a clock and other reminders of date/time
  • Familiar objects where possible
  • Involvement of family, friends, carers
  • Control noise level around patient
  • Adequate lighting and temperature
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12
Q

What is the medical management of delirium?

A
  1. Haloperidol (oral, IV, IM) –> do not give to Parkinson patients
  2. Lorazepam
  3. Levomepromazine –> do not give to Parkinson patients
  4. Quetiapine –> Parkinson’s disease
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