Delayed puberty Flashcards

1
Q

no pubertal development by the age of […] in boys and […] in girls.

A

no pubertal development by the age of 15 in boys and 14 in girls.

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2
Q

Most common cause

A

constitutional delay of growth and puberty, in which children are ‘late bloomers’ and enter normal puberty later than their peers. They will eventually reach full normal height and development.

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3
Q

Dx of constitutional delay

A

hand-wrist X-ray –> confirm bone age, –> delayed in constitutional bone delay (epiphyseal plates are late to fuse)

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4
Q

Low gonadotrophin

Low gonadotrophin secretion induces pituitary disorders ([…], […] syndrome, panhypopituitarism or isolated […] deficiency), […], or systemic disease (e.g. […] […] or Crohn’s).

A

Low gonadotrophin secretion induces pituitary disorders (craniopharyngiomas, Kallmann syndrome, panhypopituitarism or isolated gonadotrophin deficiency), hypothyroidism, or systemic disease (e.g. cystic fibrosis or Crohn’s).

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5
Q

High gonadotrophin secretion causes include […] disorders ([…] XO, […] XXY), […] […] […] , or acquired […] (e.g. after chemotherapy)

A

High gonadotrophin secretion causes include chromosomal disorders (Turner’s XO, Klinefelter’s XXY), congenital adrenal hyperplasia, or acquired hypogonadism (e.g. after chemotherapy)

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