degenerative neuro Flashcards
what is myasthenia gravis?
autoimmune disease that is characterized by varying degrees of the voluntary muscles causing muscle weakness
what body parts are effected?
muscles, eye muscles, throat muscles, arms, legs, and severe respiratory muscles fall
how does the thymus gland effect MG?
the thymus gland produces T cells, and then attacks them
risk factors for M.G.?
female (<40)
male (>60)
what can worsen MG?
fatigue
Illness
Stress
Extreme
signs and symptoms of MG?
diplopia
Ptosis
weakness of face, throat and general area
What type of disorder is MG?
A motor disorder
what is the tensilon test?
injection of the chemical edrophonium, which once injected may result in a sudden increase of muscle strength
what is edrophonium?
an acetylcholinesterase inhibitor, prevents the breakdown of acetylcholine.
what does the tensilion test show?
that the patient has MG
what are the adverse effects fo edrophonium?
bradycardia, systole, increased oral and bronchial secretions, and bronchoconstriction
diagnosing MG?
EMG
CT of chest to look at the Thymus
Tensilon test
treatment of MG?
supportive care
IVIG- replace antibodies
anticholinesterase medications
thymectomy- remove thymus
what is MS?
multiple sclerosis
unpredictable and disabling disease of the CNS that disrupts the flow of info within the brain and between the brain and body
causes a damaged myelin sheath
causes of MS?
idiopathic, possibly genetic
when are people diagnosed with MS?
between the ages of 20-50
symptoms of MS?
weakness tingling numbness blurred vision muscle stiffness thinking problems urinary problems
what may MS be misdiagnosed as?
a CVA
what can MS be triggered by?
a viral infection, but this is not always the case.
how is MS diagnosed?
by process of elimination,
MRI can reveal plaques in the brain and spinal cord
treatment of MS
focus is on speeding recovery from attacks, and slowing progression of disease
corticosteroids
plasmapheresis